Could a Baby's cord blood predict leukemia years later?

NCT ID NCT05014165

First seen Jun 27, 2026 ยท Last updated Jun 27, 2026

Summary

This study collects stored cord blood from 300 children diagnosed with leukemia and checks for the same cancer mutations found in their tumor samples. Researchers want to understand how and when these mutations first appear before birth. The goal is to eventually develop a screening test that could detect pre-leukemia cells in newborns.

What this could mean

Our plain-language read of the trial. This is informational only โ€” not medical advice or a prediction.

What this could lead to
If successful, this could lead to a simple blood test to detect pre-leukemia cells at birth, allowing early monitoring or prevention.
What could go wrong
This is an observational study, not a treatment trial. It may not find mutations in all samples, and a screening test is still years away.

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Conditions

The condition(s) this trial relates to.

acute lymphoblastic leukemia acute myeloid leukemia Precursor Cell Lymphoblastic Leukemia-Lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • University of Minnesota/Masonic Cancer Center

    RECRUITING

    Minneapolis, Minnesota, 55455, United States

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