Engineered immune cells take on Hard-to-Treat ovarian cancer in first human test
NCT ID NCT06305299
First seen Nov 01, 2025 · Last updated May 23, 2026 · Updated 27 times
Summary
This early-phase study tests whether a new treatment using a patient's own modified immune cells (called CAR T cells) is safe for women with ovarian cancer that came back after standard platinum-based chemotherapy. The cells are designed to target a protein called B7-H3 found on cancer cells and include a safety switch to stop them if needed. About 27 participants will receive the cells after a short chemotherapy course to help them work better. The main goal is to find the safest dose and watch for side effects.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Lineberger Comprehensive Cancer Center
RECRUITINGChapel Hill, North Carolina, 27599, United States
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