New combo therapy shows promise in brain cancer trial

NCT ID NCT05635734

First seen Feb 05, 2026 · Last updated Jun 12, 2026 · Updated 21 times

Summary

This study tested whether adding the drug azeliragon to standard radiation and chemotherapy (temozolomide) is safe and shows early signs of working in people with newly diagnosed glioblastoma, a fast-growing brain cancer. 33 participants received the combination. The main goals were to find the best dose and check for side effects. Results help guide future larger studies.

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Contacts and locations

Locations

  • Hospital Clínic de Barcelona

    Barcelona, Barcelona, 08036, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, Madrid, 28034, Spain

  • Hospital del Mar

    Barcelona, Barcelona, 08003, Spain

Conditions

Explore the condition pages connected to this study.