New combo therapy shows promise in brain cancer trial

NCT ID NCT05635734

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 1 time

Summary

This study tested whether adding the drug azeliragon to standard radiation and chemotherapy (temozolomide) is safe and shows early signs of working in people with newly diagnosed glioblastoma, a fast-growing brain cancer. 33 participants received the combination. The main goals were to find the best dose and check for side effects. Results help guide future larger studies.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Hospital Clínic de Barcelona

    Barcelona, Barcelona, 08036, Spain

  • Hospital Universitario 12 de Octubre

    Madrid, Madrid, 28041, Spain

  • Hospital Universitario Ramon y Cajal

    Madrid, Madrid, 28034, Spain

  • Hospital del Mar

    Barcelona, Barcelona, 08003, Spain

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