New drug shows promise for Crohn's sufferers in Mid-Stage trial

NCT ID NCT06450197

Ongoing Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 10, 2026 · Updated 2 times

Summary

This study tests a new drug called AZD7798 in 120 people with moderate to severe Crohn's disease. The goal is to see if it can reduce symptoms and improve the appearance of the gut lining. Participants are randomly assigned to receive either the drug or a placebo, and neither they nor their doctors know which they get. The trial is currently active but not recruiting new participants.

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Conditions

The condition(s) this trial relates to.

Crohn disease Inflammation

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MODERATE TO SEVERE CROHN'S DISEASE

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Phoenix, Arizona, 85054, United States
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Escondido, California, 92025, United States
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La Jolla, California, 92037, United States
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Victorville, California, 92395, United States
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Hamden, Connecticut, 06518, United States
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Orlando, Florida, 32825, United States
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Tampa, Florida, 33607, United States
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Idaho Falls, Idaho, 83404, United States
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Kansas City, Kansas, 66160, United States
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Clinton Township, Michigan, 48038, United States
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Liberty, Missouri, 64068, United States
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St Louis, Missouri, 63156, United States
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Asheville, North Carolina, 28803, United States
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Charlotte, North Carolina, 28204, United States
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Winston-Salem, North Carolina, 27103, United States
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Uniontown, Pennsylvania, 15401, United States
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Dallas, Texas, 75246, United States
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Garland, Texas, 75044, United States
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Mansfield, Texas, 76063, United States
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San Antonio, Texas, 78229, United States
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CABA, 1125, Argentina
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CABA, C1025ABI, Argentina
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Ciudad Autonoma de Bs As, C1013AAB, Argentina
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Ciudad de Buenos Aires, 1128, Argentina
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San Miguel de Tucumán, 4000, Argentina
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Adelaide, 5000, Australia
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Box Hill, 3128, Australia
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Epping, 3076, Australia
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Fitzroy, 3065, Australia
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Heidelberg, 3084, Australia
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Melbourne, 3004, Australia
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Parkville, 3050, Australia
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South Brisbane, QLD 4101, Australia
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Wollongong, 2500, Australia
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Aalst, 9300, Belgium
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Ghent, 9000, Belgium
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Leuven, 3000, Belgium
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Liège, 4000, Belgium
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Campinas, 13092133, Brazil
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Jaú, 17201-130, Brazil
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Porto Alegre, 90035-903, Brazil
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Santo André, 09080-110, Brazil
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São José do Rio Preto, 15090-000, Brazil
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São Paulo, 04543-011, Brazil
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Gorna Oryahovitsa, 5100, Bulgaria
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Sofia, 1680, Bulgaria
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Sofia, 1784, Bulgaria
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Lethbridge, Alberta, T1J4G9, Canada
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Vaughan, Ontario, L4L 4Y7, Canada
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Santiago, 7500010, Chile
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Santiago, 7691236, Chile
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Santiago, 8330034, Chile
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Viña del Mar, 2540488, Chile
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Beijing, CN-100730, China
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Chengdu, 610041, China
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Guangzhou, 510080, China
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Guangzhou, 510655, China
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Hangzhou, 310016, China
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Nanchang, 330006, China
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Nanjing, 210029, China
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Wuhan, 430030, China
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Amiens, 88054, France
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Lille, 59037, France
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Montpellier, 34090, France
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Pierre-Bénite, 69495, France
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Vandœuvre-lès-Nancy, 54500, France
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Berlin, 14163, Germany
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Halle, 06108, Germany
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Jena, 07747, Germany
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Kiel, 24105, Germany
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Potsdam, 14467, Germany
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Ulm, 89081, Germany
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Békéscsaba, 5600, Hungary
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Budapest, 1082, Hungary
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Gyöngyös, 3200, Hungary
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Florence, 50134, Italy
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Milan, 20132, Italy
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Milan, 20157, Italy
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Roma, 00128, Italy
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Roma, 00152, Italy
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Rome, 00168, Italy
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Hiroshima, 734-8551, Japan
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Kashiwa-shi, 277-0871, Japan
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Kure-shi, 737-8505, Japan
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Minatoku, 108-8642, Japan
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Nagasaki, 852-8501, Japan
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Nagoya, 466-8560, Japan
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Sakura-shi, 285-8741, Japan
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Sapporo, 060-8543, Japan
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Sendai, 980-8574, Japan
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Johor Bahru, 80100, Malaysia
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Kota Bharu, 15586, Malaysia
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Kota Kinabalu, 88200, Malaysia
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Kuala Lumpur, 59100, Malaysia
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Kuching, 93586, Malaysia
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Amsterdam, 1081 HZ, Netherlands
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Nijmegen, 6525 GA, Netherlands
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Tilburg, 5022, Netherlands
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Bydgoszcz, 85-229, Poland
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Chojnice, 89-600, Poland
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Krakow, 30-363, Poland
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Lublin, 20-582, Poland
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Poznan, 60-529, Poland
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Poznan, 61-731, Poland
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Sopot, 81-756, Poland
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Warsaw, 00-189, Poland
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Warsaw, 04-501, Poland
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Wroclaw, 53-149, Poland
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Bucharest, 011461, Romania
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Bucharest, 013812, Romania
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Bucharest, 020125, Romania
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Cluj-Napoca, 400380, Romania
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Timișoara, 300002, Romania
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Košice, 04013, Slovakia
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Nitra, 94901, Slovakia
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Prešov, 08001, Slovakia
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Trnava, 91702, Slovakia
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Assagay, 3610, South Africa
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Plumstead, 7800, South Africa
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Alicante, 03010, Spain
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Barcelona, 08022, Spain
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Las Palmas de Gran Canaria, 35010, Spain
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Madrid, 28046, Spain
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Seville, 41013, Spain
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Linköping, 58185, Sweden
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Stockholm, 11630, Sweden
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New Taipei City, 24352, Taiwan
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Taichung, 40447, Taiwan
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Taipei, 10002, Taiwan
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Taoyuan, 333, Taiwan
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Ankara, 06800, Turkey (Türkiye)
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Ankara, 6500, Turkey (Türkiye)
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Antalya, 07100, Turkey (Türkiye)
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Bursa, 16059, Turkey (Türkiye)
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Izmir, 35100, Turkey (Türkiye)
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İzmit, 41000, Turkey (Türkiye)
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Malatya, 44280, Turkey (Türkiye)
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Chernivtsі, 58022, Ukraine
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Kiev, 02000, Ukraine
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Kyiv, 03680, Ukraine
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Kyiv, 04210, Ukraine
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Ternopil, 46000, Ukraine
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Vinnytsia, 21001, Ukraine
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Vinnytsia, 21009, Ukraine
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Hanoi, 10000, Vietnam
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Hà Nội, 100000, Vietnam
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Ho Chi Minh City, 700000, Vietnam
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Hồ Chí Minh, 700000, Vietnam