New drug tested in patients with liver disease – safety first

NCT ID NCT06812780

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study looked at how the drug AZD2389 behaves in people with liver impairment compared to healthy volunteers. 35 adults took a single dose, and researchers measured drug levels in the blood to check safety and processing. The goal is to understand if liver problems change how the drug works, which helps guide future dosing.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AZD2389

What this could lead to

If successful, this study could help doctors determine the right dose of AZD2389 for patients with liver disease, making the drug safer to use.

What could go wrong

This is an early-stage study with only 35 participants. It focuses on how the body handles the drug, not on treating a disease, so it may not lead to a new treatment.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

cirrhosis of liver follicular lymphoma liver disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Research Site

    Chandler, Arizona, 85225, United States

  • Research Site

    Rialto, California, 92377, United States

  • Research Site

    Miami Lakes, Florida, 33014, United States

  • Research Site

    Orlando, Florida, 32809, United States

  • Research Site

    San Antonio, Texas, 78215, United States