New combo therapy shows promise for Hard-to-Treat cancers

NCT ID NCT02617277

First seen Nov 17, 2025 · Last updated May 15, 2026 · Updated 22 times

Summary

This early-phase study tested a new combination of two drugs, AZD1775 (a pill) and durvalumab (given by IV), in 56 adults with advanced solid tumours that had stopped responding to standard treatments. The main goal was to check the safety and side effects of the combination, and to see how the body processes the drugs. While not a cure, the study aimed to find a safe dose and gather early signs of tumour control.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Research Site

    Denver, Colorado, 80218, United States

  • Research Site

    Sarasota, Florida, 34232, United States

  • Research Site

    Nashville, Tennessee, 37203, United States

Conditions

Explore the condition pages connected to this study.