New drug AZD0486 shows promise in early trial for blood cancers

NCT ID NCT06564038

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Nov 01, 2025 · Last updated May 15, 2026 · Updated 28 times

Summary

This study is testing a new drug called AZD0486, either by itself or with other cancer treatments, in people with certain types of blood cancers like chronic lymphocytic leukemia and lymphoma. The main goals are to check if the drug is safe and to find the best dose. About 408 participants will take part in this early-phase trial.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

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Study contacts

Contact

Phone: •••-•••-•••• Email: •••••@•••••

Locations

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Boston, Massachusetts, 02215, United States
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Hackensack, New Jersey, 07601, United States
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New Brunswick, New Jersey, 08901, United States
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New York, New York, 10029, United States
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WITHDRAWN

New York, New York, 10065, United States
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Charlotte, North Carolina, 28204, United States
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Charlotte, North Carolina, 28204, United States
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Columbus, Ohio, 43210, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Providence, Rhode Island, 02903, United States
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Houston, Texas, 77030, United States
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Heidelberg, 3084, Australia
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Melbourne, 3004, Australia
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Nedlands, 6009, Australia
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Beijing, 100044, China
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Guangzhou, 510060, China
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WITHDRAWN

Jinan, 250013, China
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Tianjin, 300060, China
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Zhengzhou, 450008, China
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Ostrava - Poruba, 708 52, Czechia
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Prague, 12808, Czechia
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Praha 2 - Nové Město, 12820, Czechia
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Aalborg, 9000, Denmark
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Aarhus N, 8200, Denmark
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Copenhagen, 2100, Denmark
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Odense C, 5000, Denmark
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Clermont-Ferrand, 63000, France
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Montpellier, 34295, France
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Paris, 75010, France
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Saint-Cloud, 92210, France
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Villejuif, 94805, France
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Cologne, 50937, Germany
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Homburg, 66421, Germany
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Kiel, 24105, Germany
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Mainz, 55131, Germany
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München, 81377, Germany
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Würzburg, 97080, Germany
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Bologna, 40138, Italy
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Milan, 20141, Italy
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Kōtoku, 135-8550, Japan
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Matsuyama, 791-0280, Japan
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Nagoya, 464-8681, Japan
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Busan, 48108, South Korea
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Seoul, 02841, South Korea
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Seoul, 03080, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Barcelona, 8036, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Palma de Mallorca, 7120, Spain
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Santiago de Compostela, 15706, Spain
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Valencia, 46026, Spain
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Changhua, 500, Taiwan
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Kaohsiung City, 83301, Taiwan
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Tainan, 710, Taiwan
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Taipei, 100, Taiwan
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Derriford, PL6 5FP, United Kingdom
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London, SE5 9RS, United Kingdom
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Oxford, 0X3 7LJ, United Kingdom
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Southampton, SO16 6YD, United Kingdom

Conditions

Explore the condition pages connected to this study.

B-CELL NON HODGKIN LYMPHOMA B-CELL NON HODGKIN LYMPHOMA CHRONIC LYMPHOCYTIC LEUKAEMIA LARGE B-CELL LYMPHOMA MANTLE CELL LYMPHOMA SMALL LYMPHOCYTIC LYMPHOMA