New drug combo trial targets blood cancers

NCT ID NCT06564038

Recruiting now Disease control Sponsor: AstraZeneca Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Aug 13, 2026 · Updated 4 times

Summary

This study tests a new drug called AZD0486, alone or with other cancer drugs, in people with B-cell blood cancers like certain lymphomas and leukemias. The goal is to see if it is safe and helps shrink or control the cancer. About 408 adults will take part in this early-phase trial.

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Conditions

The condition(s) this trial relates to.

B-cell chronic lymphocytic leukemia B-cell neoplasm B-cell non-Hodgkin lymphoma large B-cell lymphoma Leukemia, B-Cell mantle cell lymphoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

B-CELL NON-HODGKIN LYMPHOMA CHRONIC LYMPHOCYTIC LEUKAEMIA LARGE B-CELL LYMPHOMA MANTLE CELL LYMPHOMA SMALL LYMPHOCYTIC LYMPHOMA

Contacts and locations

Locations

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Boston, Massachusetts, 02215, United States
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Hackensack, New Jersey, 07601, United States
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New Brunswick, New Jersey, 08901, United States
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New York, New York, 10029, United States
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New York, New York, 10065, United States
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Charlotte, North Carolina, 28204, United States
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Charlotte, North Carolina, 28204, United States
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Columbus, Ohio, 43210, United States
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Portland, Oregon, 97239, United States
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Philadelphia, Pennsylvania, 19104, United States
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Pittsburgh, Pennsylvania, 15232, United States
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Providence, Rhode Island, 02903, United States
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Houston, Texas, 77030, United States
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Heidelberg, 3084, Australia
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Melbourne, 3004, Australia
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Nedlands, 6009, Australia
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Beijing, 100044, China
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Guangzhou, 510060, China
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Jinan, 250013, China
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Tianjin, 300060, China
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Zhengzhou, 450008, China
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Ostrava - Poruba, 708 52, Czechia
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Prague, 12808, Czechia
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Praha 2 - Nové Město, 12820, Czechia
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Aalborg, 9000, Denmark
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Aarhus N, 8200, Denmark
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Copenhagen, 2100, Denmark
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Odense C, 5000, Denmark
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Clermont-Ferrand, 63000, France
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Montpellier, 34295, France
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Paris, 75010, France
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Saint-Cloud, 92210, France
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Villejuif, 94805, France
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Cologne, 50937, Germany
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Homburg, 66421, Germany
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Kiel, 24105, Germany
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Mainz, 55131, Germany
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München, 81377, Germany
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Würzburg, 97080, Germany
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Bologna, 40138, Italy
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Milan, 20141, Italy
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Kōtoku, 135-8550, Japan
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Matsuyama, 791-0280, Japan
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Nagoya, 464-8681, Japan
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Busan, 48108, South Korea
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Seoul, 02841, South Korea
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Seoul, 03080, South Korea
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Seoul, 05505, South Korea
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Seoul, 06351, South Korea
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Seoul, 06591, South Korea
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Barcelona, 8036, Spain
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Madrid, 28034, Spain
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Madrid, 28040, Spain
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Palma de Mallorca, 7120, Spain
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Santiago de Compostela, 15706, Spain
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Valencia, 46026, Spain
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Changhua, 500, Taiwan
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Kaohsiung City, 83301, Taiwan
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Tainan, 710, Taiwan
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Taipei, 100, Taiwan
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Derriford, PL6 5FP, United Kingdom
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London, SE5 9RS, United Kingdom
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Oxford, 0X3 7LJ, United Kingdom
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Southampton, SO16 6YD, United Kingdom

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