First human test of new pill targets 'Undruggable' cancer mutation

NCT ID NCT06599502

Summary

This early-stage study tested a new oral drug, AZD0022, alone and combined with another cancer drug, in people with advanced solid tumors driven by a specific genetic change called KRASG12D. The main goals were to find a safe dose and see if the treatment caused any side effects. The study was terminated early after enrolling 17 participants.

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Contacts and locations

Locations

  • Research Site

    Duarte, California, 91010, United States

  • Research Site

    New York, New York, 10016, United States

  • Research Site

    Fairfax, Virginia, 22031, United States

  • Research Site

    Melbourne, 3000, Australia

  • Research Site

    Chūōku, 104-0045, Japan

  • Research Site

    Seoul, 03080, South Korea

Conditions

Explore the condition pages connected to this study.