New cancer drug trial halted after just 3 patients

NCT ID NCT07159828

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This early-stage trial tested a new drug called AXN-2510 in adults with advanced solid tumors that had stopped responding to other treatments. The drug is a special antibody that targets two cancer pathways at once. However, the study was terminated early after enrolling only 3 participants, so we have very little information about its safety or effectiveness.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AXN-2510 (a bispecific antibody that blocks PD-L1 and inhibits VEGF)

What this could lead to

If successful, this could point toward a new treatment option for advanced solid tumors that have not responded to other therapies.

What could go wrong

This was a very early, small Phase 1 trial that was terminated after only 3 participants. It is too early to know if the drug is safe or effective, and many early-stage cancer drugs never reach patients.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

neoplasm

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Carolina BioOncology

    Huntersville, North Carolina, 28078, United States

  • NEXT Houston

    Houston, Texas, 77054, United States

  • NEXT San Antonio

    San Antonio, Texas, 78229, United States

  • NEXT Virginia

    Fairfax, Virginia, 22031, United States

  • New Experimental Therapeutics (NEXT) Oncology - Houston

    Houston, Texas, 77054, United States

  • New Experimental Therapeutics of San Antonio - NEXT Oncology

    San Antonio, Texas, 78229, United States

  • Sarah Cannon Research Institute at Mary Crowley

    Dallas, Texas, 75251, United States