New pill shows promise against Hard-to-Treat cancers

NCT ID NCT05867251

First seen Nov 01, 2025 · Last updated May 14, 2026 · Updated 32 times

Summary

This study tests a new oral drug, AVZO-021, in people with advanced solid tumors that have not responded to other treatments. The drug targets a protein called CDK2 to slow or stop cancer growth. The trial has two phases: first to find the safest dose, then to see if it shrinks tumors or delays progression in specific cancers like breast, ovarian, and endometrial cancer.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Cancer Care Wollongong

    RECRUITING

    Wollongong, New South Wales, Australia

    Contact

  • Florida Cancer Specialists

    RECRUITING

    Sarasota, Florida, 34232, United States

    Contact

  • Macquarie University Hospital

    RECRUITING

    Macquarie University, New South Wales, Australia

    Contact

  • Moffitt Cancer Center

    RECRUITING

    Tampa, Florida, 33612, United States

    Contact

  • NEXT Virginia

    RECRUITING

    Fairfax, Virginia, 22031, United States

    Contact

  • NYU Langone Medical Center (Tisch Hospital)

    RECRUITING

    New York, New York, 10016, United States

    Contact

  • Oklahoma University

    RECRUITING

    Oklahoma City, Oklahoma, 73117, United States

    Contact

  • Perlmutter Cancer Center at NYU Langone Hospital - Long Island

    RECRUITING

    Mineola, New York, 11501, United States

    Contact

  • Providence Cancer Institute

    RECRUITING

    Portland, Oregon, 97213, United States

    Contact

  • Sidney Kimmel Cancer Center (SKCC) at Jefferson Health

    RECRUITING

    Philadelphia, Pennsylvania, 19107, United States

    Contact

  • Texas Oncology - DFW

    RECRUITING

    Dallas, Texas, 75246, United States

    Contact

  • University Hospitals Cleveland Medical Center

    RECRUITING

    Cleveland, Ohio, 44106, United States

    Contact

  • Yale Cancer Center

    RECRUITING

    New Haven, Connecticut, 06520, United States

    Contact

Conditions

Explore the condition pages connected to this study.