New drug combo aims to tackle tough blood cancer
NCT ID NCT06327685
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This early-phase study tests a combination of two drugs, avapritinib and decitabine, for people with a rare blood cancer called systemic mastocytosis with an associated hematologic neoplasm (SM-AHN). The goal is to find a safe dose that can control both parts of the disease. About 34 adults will take part to see how well the combination works and what side effects occur.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Dana-Farber Cancer Institute
NOT_YET_RECRUITINGBoston, Massachusetts, 02215, United States
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Mayo Clinic - Arizona
NOT_YET_RECRUITINGPhoenix, Arizona, 85054, United States
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Memorial Sloan Kettering Cancer Center
NOT_YET_RECRUITINGNew York, New York, 10065, United States
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Moffitt Cancer Center
RECRUITINGTampa, Florida, 33612, United States
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Contact Phone: •••-•••-•••• Email: •••••@•••••
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Stanford University Medical Center
NOT_YET_RECRUITINGPalo Alto, California, 94305, United States
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University of Michigan
NOT_YET_RECRUITINGAnn Arbor, Michigan, 48109, United States
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University of Utah Health
RECRUITINGSalt Lake City, Utah, 84132, United States
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