New hope for mastocytosis patients: expanded access to bezuclastinib
NCT ID NCT06915766
First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This program provides the investigational drug bezuclastinib to adults with systemic mastocytosis who have failed or cannot tolerate standard treatments. Participants must be at least 18 years old and able to swallow tablets. The goal is to offer a potential treatment option when no satisfactory alternatives exist.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
bezuclastinib (also known as CGT9486)
What this could lead to
If this drug works, it could offer a new treatment option for patients with systemic mastocytosis who have run out of standard therapies.
What could go wrong
This is an expanded access program, not a formal trial, so data on effectiveness and safety is still limited. The drug may not work for everyone and could cause side effects.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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AIR Care
AVAILABLEDallas, Texas, 75231, United States
Contact Email: •••••@•••••
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AllerVie Health
AVAILABLEGlenn Dale, Maryland, 20769, United States
Contact Email: •••••@•••••
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Allergy Associates of Utah
AVAILABLESandy City, Utah, 84093, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Boston Specialists
AVAILABLEBoston, Massachusetts, 02111, United States
Contact Email: •••••@•••••
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Dana Farber Cancer Institute
AVAILABLEBoston, Massachusetts, 02215, United States
Contact Email: •••••@•••••
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Dartmouth-Hitchcock Medical Center
AVAILABLELebanon, New Hampshire, 03756, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Duke Blood Cancer Center
AVAILABLEDurham, North Carolina, 27705, United States
Contact Email: •••••@•••••
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Indiana University Health
AVAILABLEIndianapolis, Indiana, 46202, United States
Contact Email: •••••@•••••
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Mayo Clinic
AVAILABLERochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Memorial Sloan Kettering Cancer Center
AVAILABLENew York, New York, 10065, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Michigan Medicine- University of Michigan
AVAILABLEAnn Arbor, Michigan, 48109, United States
Contact Email: •••••@•••••
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Northern Light Eastern Maine Medical Center
AVAILABLEBangor, Maine, 04401, United States
Contact Phone: •••-•••-••••
Contact Email: •••••@•••••
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Northwest Medical Specialties
AVAILABLETacoma, Washington, 98405, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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Orso Health/Modena Asthma Allergy
AVAILABLELa Jolla, California, 92037, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact
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Scripps Green Hospital
AVAILABLELa Jolla, California, 92037, United States
Contact Email: •••••@•••••
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Sneeze Wheeze & Itch Associates LLC Clinical Research Center
AVAILABLENormal, Illinois, 61761, United States
Contact Phone: •••-•••-••••
Contact Phone: •••-•••-••••
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Texas Children's Hospital
AVAILABLEHouston, Texas, 77030, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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The Ohio State University Wexner Medical Center
AVAILABLEColumbus, Ohio, 43210, United States
Contact Email: •••••@•••••
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The University of Texas, MD Anderson Cancer Center
AVAILABLEHouston, Texas, 77030, United States
Contact Email: •••••@•••••
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UCLA Ronald Reagan Medical Center
AVAILABLELos Angeles, California, 90095, United States
Contact Phone: •••-•••-••••
Contact Email: •••••@•••••
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Walter Reed
AVAILABLEBethesda, Maryland, 20889, United States
Contact Email: •••••@•••••
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Washington University School of Medicine in St. Louis
AVAILABLESt Louis, Missouri, 63110, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••