Smart chemo targets tumors, spares healthy tissue in early trial

NCT ID NCT04969835

First seen Nov 01, 2025 · Last updated May 09, 2026 · Updated 28 times

Summary

This early-phase study tests a new drug called AVA6000, a chemotherapy that is designed to activate only inside tumors, potentially reducing side effects. It is for people with advanced solid tumors (like breast, ovarian, or salivary gland cancer) that have not responded to standard treatments. The main goals are to check safety, find the right dose, and see early signs of tumor shrinkage.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Fred Hutchinson Cancer Center

    RECRUITING

    Seattle, Washington, 98109, United States

    Contact

  • Memorial Sloan Kettering Cancer Center

    RECRUITING

    New York, New York, 10065, United States

    Contact

  • St James's University Hospital, The Leeds Teaching Hospitals NHS Trust

    RECRUITING

    Leeds, LS9 7TF, United Kingdom

    Contact

  • The Beatson West of Scotland Cancer Centre, NHS Greater Glasgow & Clyde

    RECRUITING

    Glasgow, G12 0YN, United Kingdom

    Contact

  • The Christie NHS Foundation Trust

    RECRUITING

    Manchester, M20 4BX, United Kingdom

    Contact

  • The Freeman Hospital, Newcastle-upon-Tyne NHS Foundation Trust

    RECRUITING

    Newcastle upon Tyne, NE7 7DN, United Kingdom

    Contact

  • The Royal Marsden, NHS Foundation Trust

    RECRUITING

    London, SM2 5PT, United Kingdom

    Contact

  • University of Texas MD Anderson Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

  • Weston Park Cancer Centre, Sheffield Teaching Hospitals NHS Foundation Trust

    NOT_YET_RECRUITING

    Sheffield, S10 2SJ, United Kingdom

    Contact

Conditions

Explore the condition pages connected to this study.