Anthrax vaccine and antibiotics: a safety check

NCT ID NCT04067011

First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time

Summary

This study looked at whether giving the anthrax vaccine AV7909 along with common antibiotics (ciprofloxacin or doxycycline) changes how the body processes those antibiotics. 210 healthy adults received the vaccine and antibiotics on a set schedule. The goal was to see if the vaccine affects antibiotic levels in the blood and whether the vaccine still triggers a strong immune response.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

AV7909 (anthrax vaccine with adjuvant), ciprofloxacin, doxycycline

What this could lead to

If successful, this study could confirm that the anthrax vaccine AV7909 can be safely given alongside these antibiotics without changing how well the antibiotics work.

What could go wrong

This is a small, early-phase study in healthy adults, not people with anthrax. Results may not apply to real-world infection scenarios, and the vaccine's immune response might still be affected.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

anthrax infection prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Avail Clinical Research, LLC

    DeLand, Florida, 32720, United States

  • Meridian Clinical Research, LLC

    Omaha, Nebraska, 68134, United States

  • New Orleans Center for Clinical Research / Volunteer Research Group

    Knoxville, Tennessee, 37920, United States

  • The Center for Pharmaceutical Research

    Kansas City, Missouri, 64114, United States