Anthrax vaccine and antibiotics: a safety check
NCT ID NCT04067011
First seen Jun 25, 2026 · Last updated Jun 26, 2026 · Updated 1 time
Summary
This study looked at whether giving the anthrax vaccine AV7909 along with common antibiotics (ciprofloxacin or doxycycline) changes how the body processes those antibiotics. 210 healthy adults received the vaccine and antibiotics on a set schedule. The goal was to see if the vaccine affects antibiotic levels in the blood and whether the vaccine still triggers a strong immune response.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- AV7909 (anthrax vaccine with adjuvant), ciprofloxacin, doxycycline
- What this could lead to
- If successful, this study could confirm that the anthrax vaccine AV7909 can be safely given alongside these antibiotics without changing how well the antibiotics work.
- What could go wrong
- This is a small, early-phase study in healthy adults, not people with anthrax. Results may not apply to real-world infection scenarios, and the vaccine's immune response might still be affected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Avail Clinical Research, LLC
DeLand, Florida, 32720, United States
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Meridian Clinical Research, LLC
Omaha, Nebraska, 68134, United States
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New Orleans Center for Clinical Research / Volunteer Research Group
Knoxville, Tennessee, 37920, United States
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The Center for Pharmaceutical Research
Kansas City, Missouri, 64114, United States
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