New nerve block aims to cut opioid use after colon surgery

NCT ID NCT07351994

Not yet recruiting Symptom relief Sponsor: Antonio Caycedo, MD Source: ClinicalTrials.gov ↗

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests a nerve block given during minimally invasive colorectal surgery to see if it reduces pain and the need for opioids. Researchers will track 400 adults having left-sided colon or rectal surgery. The goal is to improve recovery and reduce side effects like nausea.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: Autonomic neural field block (nerve block with local anesthetic)
What this could lead to: If successful, this nerve block could become a standard addition to pain management after colorectal surgery, reducing opioid use and speeding recovery.
What could go wrong: This is an early observational registry, not a randomized trial. The nerve block may not significantly reduce pain or opioid use, and there is a small risk of complications from the procedure itself.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

opioid abuse Pain, Postoperative Postoperative Nausea and Vomiting

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

OPIOID USE POSTOPERATIVE NAUSEA POSTOPERATIVE PAIN

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