Stool transplants via stoma show promise for treating Post-Surgery colon inflammation

NCT ID NCT07674186

First seen Jun 29, 2026 · Last updated Jun 30, 2026 · Updated 1 time

Summary

This study tests whether giving patients their own stool bacteria through a temporary stoma can reduce inflammation in the unused part of the colon, a condition called diversion colitis. Sixty-six people with rectal cancer who have a temporary ileostomy will receive either a daily fecal bacteria infusion or a saltwater rinse for four weeks. Researchers will measure changes in inflammation using a camera and tissue samples, and track bowel function and quality of life after the stoma is reversed.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

autologous fecal microbiota (own stool bacteria)

What this could lead to

If it works, this could offer a simple, drug-free way to treat diversion colitis and improve bowel function after stoma reversal.

What could go wrong

This is a small, early-stage trial with 66 participants. The treatment may not reduce inflammation better than saline, and long-term benefits are unproven.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

diversion colitis rectum adenocarcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Department of Colorectal Surgery, The First People's Hospital of Lin'an District, Hangzhou

    Hangzhou, Zhejiang, 311300, China