A new ultrasound measure may spot At-Risk babies in High-Blood-Pressure pregnancies
NCT ID NCT07795320
First seen Aug 31, 2026 · Last updated Sep 01, 2026 · Updated 1 time
Summary
Researchers at Assiut University are testing whether a new ultrasound measurement, the Amniotic-Umbilical-to-Cerebral Ratio (AUCR), can predict complications in newborns of women with hypertensive disorders of pregnancy. They will compare AUCR with the traditional Cerebroplacental Ratio (CPR) in 130 women with a singleton pregnancy at 32 weeks or later. The main goal is to see which ratio better identifies babies who need neonatal intensive care shortly after birth. If AUCR proves more accurate, it could help doctors plan deliveries and newborn care more effectively.
What this could mean
Our plain-language read of the trial. This is informational only, not medical advice or a prediction.
- Active substance
- Ultrasound-based measurement of the Amniotic-Umbilical-to-Cerebral Ratio (AUCR) compared with the Cerebroplacental Ratio (CPR)
- What this could lead to
- If AUCR proves more accurate than CPR, doctors could better identify which babies of mothers with high blood pressure need intensive care, allowing earlier and more targeted monitoring.
- What could go wrong
- This is a single-center study with 130 participants, and the new ratio may not outperform the standard one. Ultrasound measurements can vary between operators, and results may not apply to all pregnancies.
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Study facts
What this study's own registry entry says, in plain language.
- Participants
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About 130 people
The number the study aims to enrol. It can still change while the study runs.
- Expected to start
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Nov 2026
An estimate. Start dates often move.
- Expected to finish
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Apr 2028
An estimate. End dates often move.
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
Who is studied
pregnant women with hypertensive disorder
- Ages
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18 to 40 years
- Sex
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Female participants only
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion Criteria: * Women aged 18-40 years, inclusive. * Singleton viable pregnancy. * Gestational age ≥32 weeks. * Pregnancy complicated by a hypertensive disorder. * Women who provide written informed consent. Exclusion Criteria: * Multiple gestation. * Fetuses with known chromosomal or major congenital anomalies. * Maternal diseases likely to independently affect fetal circulation or perinatal outcome, such as significant cardiac disease or other major systemic diseases. * Inability to complete the required follow-up.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
How to take part
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The official record
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