Can vitamin a derivative revive failed myeloma treatment?

NCT ID NCT06536413

First seen Apr 06, 2026 · Last updated May 16, 2026 · Updated 6 times

Summary

This study tests whether adding a vitamin A derivative (ATRA) to standard carfilzomib therapy can make the cancer respond again in people with multiple myeloma that has stopped responding to carfilzomib. About 42 adults who have tried at least three prior treatments will receive the combination. The goal is to find a safe dose and see if it shrinks tumors or slows the disease.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Houston Methodist Neal Cancer Center

    RECRUITING

    Houston, Texas, 77030, United States

    Contact

Conditions

Explore the condition pages connected to this study.