New drug aims to restore joy for those whose depression resists treatment

NCT ID NCT06514742

Summary

This study tested whether adding an experimental drug called aticaprant to a person's current antidepressant could better treat major depression, specifically for people who struggle with severe anhedonia—the inability to feel pleasure. It involved 101 adults whose depression had not improved enough on standard medications. The trial was a Phase 3 study but was terminated early, so its final results are not available.

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes NO responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • ATP Clinical Research

    Orange, California, 92866, United States

  • Accelerated Clinical Trials LLC

    Peachtree Corners, Georgia, 30071, United States

  • Advanced Research Center Inc

    Anaheim, California, 92805, United States

  • Affecta Pskyiatrimottagning

    Halmstad, SE-30248, Sweden

  • Anima

    Alken, 3570, Belgium

  • BR Trials

    São Paulo, 01236030, Brazil

  • Behavioral Research Specialists LLC

    Glendale, California, 91206, United States

  • Best Choice Medical and Research Service

    Pembroke Pines, Florida, 33024, United States

  • Brain Health Consultants

    Houston, Texas, 77046, United States

  • Bugat Pal Korhaz

    Gyöngyös, 3200, Hungary

  • CBH Health

    Gaithersburg, Maryland, 20877, United States

  • CI Trials

    Bellflower, California, 90706, United States

  • Centre Hospitalier Specialise Notre Dame Des Anges Asbl

    Liège, 4000, Belgium

  • Centre for Mental Health Prof.N.Shipkovenski EOOD

    Sofia, 1377, Bulgaria

  • Centro Integrado Facili

    São Bernardo do Campo, 09726 150, Brazil

  • Centro Salud Mental La Corredoria

    Oviedo, 33011, Spain

  • Centrum Badan Klinicznych PI House sp z o o

    Gdansk, 80 546, Poland

  • Centrum Zdrowia Alcea

    Gdansk, 80 283, Poland

  • Chu Tivoli

    La Louvière, 7100, Belgium

  • Clinical Research Services Turku - CRST

    Turku, 20520, Finland

  • Conrad Clinical Research

    Edmond, Oklahoma, 73013, United States

  • Corporacio Sanitari Parc Tauli

    Sabadell, 08208, Spain

  • DelRicht Research

    New Orleans, Louisiana, 70115, United States

  • Dr Mathe es Tarsa Bt

    Kalocsa, 6300, Hungary

  • Elligo Independent Research Sites Mindful Behavioral Health

    Boca Raton, Florida, 33431, United States

  • Eszak Budai Szent Janos Centrumkorhaz

    Budapest, 1125, Hungary

  • Fieve Clinical Research Inc

    New York, New York, 10017, United States

  • Floridian Clinical Research LLC

    Miami, Florida, 33135, United States

  • Ginemedica Sp. z o.o.

    Wroclaw, 50-414, Poland

  • Gulfcoast Medical Research Center

    Fort Myers, Florida, 33912, United States

  • Gyor Moson Sopron Varmegyei Petz Aladar Egyetemi Oktato Korhaz

    Győr, 9024, Hungary

  • Hosp. Alvaro Cunqueiro

    Vigo, 36312, Spain

  • Hosp. Prov. de Zamora

    Zamora, 49021, Spain

  • Hosp. Virgen Del Rocio

    Seville, 41013, Spain

  • Hosp. de La Santa Creu I Sant Pau

    Barcelona, 08025, Spain

  • Hospital Ramon y Cajal

    Madrid, 28034, Spain

  • Humanity Clinical Research Corp

    Aventura, Florida, 33180, United States

  • IMA Clinical Research PC

    Phoenix, Arizona, 85012, United States

  • Institucion Hosp Hestia Palau

    Barcelona, 08025, Spain

  • Integrative Clinical Trials LLC

    Brooklyn, New York, 11229, United States

  • K2 Medical Research

    Tampa, Florida, 33607, United States

  • LCC Medical Research Institute Inc

    Miami, Florida, 33126, United States

  • Linkoping University Hospital

    Linköping, 58185, Sweden

  • Lumos Clinical Research Center LLC

    San Jose, California, 95124, United States

  • MCB Clinical Research Centers LLC

    Colorado Springs, Colorado, 80910, United States

  • MHC - Sofia, EOOD

    Sofia, 1202, Bulgaria

  • Meclinas

    Mechelen, 2800, Belgium

  • Medical Center Mentalcare OOD

    Plovdiv, 4004, Bulgaria

  • Medquest Translational Sciences

    Miami Lakes, Florida, 33016, United States

  • Mehilainen Finlayson

    Tampere, 33210, Finland

  • Mental Health Center Prof. Dr. Ivan Temkov

    Burgas, 8001, Bulgaria

  • NPCRS Nucleo de Pesquisa Clinica do Rio Grande do Sul

    Porto Alegre, 90430001, Brazil

  • Neuroscience Research Institute

    West Palm Beach, Florida, 33407, United States

  • New Hope Clinical Research

    Charlotte, North Carolina, 28211, United States

  • New Life Medical Research Center, Inc.

    Hialeah, Florida, 33012, United States

  • Noble Clinical Research

    Tucson, Arizona, 85704, United States

  • Northern Clinical Trial Coordinators

    Oulu, 90100, Finland

  • Northwest Clinical Research Center

    Bellevue, Washington, 98007, United States

  • OSU Department of Psychiatry and Behavioral Health

    Columbus, Ohio, 43210, United States

  • Osrodek Badan Klinicznych CLINSANTE S C

    Torun, 87 100, Poland

  • Osrodek Badan Klinicznych CLINSANTE S C Ewa Galczak Nowak Malgorzata Trzaska

    Bydgoszcz, 85 794, Poland

  • Oulu Mentalcare Oy

    Oulu, 90100, Finland

  • Patient Priority Clinical Sites LLC

    Cincinnati, Ohio, 45215, United States

  • Perceptive Pharma Research

    Richmond, Texas, 77407, United States

  • ProbarE i Lund AB

    Lund, 22222, Sweden

  • ProbarE i Stockholm AB

    Stockholm, 113 29, Sweden

  • Processus Kft

    Budapest, 1137, Hungary

  • PsychoTech Kft

    Pécs, 7633, Hungary

  • Pte Aok Pszichiatriai Klinika

    Pécs, 7623, Hungary

  • Red Oak Psychiatry Associates

    Houston, Texas, 77090, United States

  • Revival Research Institute LLC

    McKinney, Texas, 75071, United States

  • Savon Psykiatripalvelu

    Kuopio, 70110, Finland

  • Semmelweis Egyetem

    Budapest, 1083, Hungary

  • Southern Illinois University School of Medicine

    Springfield, Illinois, 62702, United States

  • Studieenheten Akademiskt Specialistcentrum Stockholm

    Stockholm, 113 61, Sweden

  • Suburban Research Associates

    Media, Pennsylvania, 19063, United States

  • Sun Valley Research Center

    Imperial, California, 92251, United States

  • Sunwise Clinical Research

    Walnut Creek, California, 94596, United States

  • Terveystalo Ruoholahti

    Helsinki, 00180, Finland

  • Tolna Varmegyei Balassa Janos Korhaz

    Szekszárd, 7100, Hungary

  • UAB Huntsville Regional Medical Campus

    Huntsville, Alabama, 35801, United States

  • UTHealth Houston Center for Interventional Psychiatry

    Houston, Texas, 77030, United States

  • Universidade Federal do Ceara Hospital Universitario Walter Cantidio

    Fortaleza, 60175 270, Brazil

  • Viking Clinical Research Ltd

    Temecula, California, 92591, United States

Conditions

Explore the condition pages connected to this study.