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Hope for elderly lung cancer patients: immunotherapy combo under study

NCT ID NCT03977194

Ongoing Disease control Sponsor: Intergroupe Francophone de Cancerologie Thoracique Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study looks at whether adding the immunotherapy drug atezolizumab to standard chemotherapy helps elderly patients (70+) with advanced non-small cell lung cancer live longer. About 510 participants will receive either chemotherapy alone or chemotherapy plus atezolizumab. The goal is to see if this combination is both effective and safe for older adults, who are often underrepresented in cancer trials.

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Conditions

The condition(s) this trial relates to.

non-small cell lung carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

NON-SMALL CELL LUNG CANCER METASTATIC

Contacts and locations

Locations

  • Abbeville - CH

    Abbeville, 80142, France

  • Aix-en-Provence - CH

    Aix-en-Provence, France

  • Annemasse - CH

    Ambilly, 74100, France

  • Auxerre - CH

    Auxerre, 89011, France

  • Avignon - CH

    Avignon, France

  • Avignon - Institut Sainte-Catherine

    Avignon, 84918, France

  • Bayonne - CH

    Bayonne, France

  • Besançon - CHU

    Besançon, France

  • Bobigny - APHP - Hôpital Avicenne

    Bobigny, France

  • Bordeaux - CHU Hôpital Haut-Lévèque

    Bordeaux, France

  • Bordeaux - Polyclinique Nord

    Bordeaux, France

  • Boulogne - Ambroise Paré

    Boulogne-Billancourt, France

  • Caen - CHU Côte de Nacre

    Caen, 14000, France

  • Cannes - CH

    Cannes, France

  • Carcassone - CH

    Carcassonne, France

  • Centre Hospitalier Mémorial de Saint-Lô

    Saint-Lô, 50000, France

  • Centre Hospitalier de Chambéry

    Chambéry, 73000, France

  • Centre Hospitalier des Pays de Morlaix

    Morlaix, 29600, France

  • Chauny - Centre Hospitalier

    Chauny, France

  • Cholet - CH

    Cholet, France

  • Clamart - Hôpital Percy

    Clamart, 92140, France

  • Clermont Ferrand - CHU

    Clermont-Ferrand, 63000, France

  • Colmar - CH

    Colmar, France

  • Cornebarrieu - Clinique des Cèdres

    Cornebarrieu, France

  • Dijon - Centre Georges-François Leclerc

    Dijon, 21000, France

  • Grenoble - CHU

    Grenoble, France

  • La Réunion - CHU (Site Sud)

    Saint-Pierre, 97448, France

  • La Réunion - CHU (site Félix GUYON)

    Saint-Denis, 97400, France

  • Le Mans - CHG

    Le Mans, France

  • Lille - GHICL

    Lille, 59020, France

  • Lille - Polyclinique de la Louvière

    Lille, France

  • Limoges - CHU

    Limoges, France

  • Lorient - CHBS

    Lorient, France

  • Lyon - Hôpital Jean Mermoz

    Lyon, France

  • Lyon - URCOT

    Pierre-Bénite, France

  • Marseille - AP-HM Hôpital Nord

    Marseille, France

  • Marseille - Hôpital Européen

    Marseille, France

  • Marseille - Institut Paoli Calmette

    Marseille, France

  • Meaux - CH

    Meaux, 77100, France

  • Metz - Thionville CHR

    Ars-Laquenexy, 57530, France

  • Montauban - CH

    Montauban, 82000, France

  • Mulhouse - GHRMSA

    Mulhouse, France

  • Nancy - Institut de Cancérologie de Lorraine

    Nancy, France

  • Nantes - CHU Hôpital Laënnec

    Nantes, France

  • Nice - CRLCC

    Nice, 06189, France

  • Orléans - CH

    Orléans, 45000, France

  • Paris - APHP - Hopital Tenon

    Paris, 75020, France

  • Paris - APHP Bichat

    Paris, France

  • Paris - Curie

    Paris, France

  • Paris - Hôpital Cochin

    Paris, France

  • Paris - Hôpital Saint Joseph

    Paris, 75014, France

  • Pau - CHG

    Pau, France

  • Quint-Fonsegrives - Clinique de la Croix du Sud

    Quint-Fonsegrives, France

  • Rodez - CH

    Rodez, 12021, France

  • Saint- Mandé - HIA Begin

    Saint-Mandé, France

  • Saint-Cloud - Centre René Huguenin

    Saint-Cloud, 92210, France

  • Saint-Etienne - CHU

    Saint-Etienne, France

  • Saint-Priest - Institut de Cancérologie de la Loire

    Saint-Priest-en-Jarez, 42271, France

  • Sens - CH

    Sens, 89100, France

  • Strasbourg - Nouvel Hôpital Civil

    Strasbourg, 67091, France

  • Suresnes - Hopital Foch

    Suresnes, 92151, France

  • Toulon - CHI

    Toulon, 83000, France

  • Toulon - HIA

    Toulon, 83000, France

  • Toulouse - CHU

    Toulouse, France

  • Tours - CHU

    Tours, 37000, France

  • Valence - CH

    Valence, 26953, France

  • Valenciennes - Clinique

    Valenciennes, 59304, France

  • Villefranche-Sur-Saône - Hôpital Nord-Ouest

    Villefranche-sur-Saône, France

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