New triple inhaler shows promise for uncontrolled asthma

NCT ID NCT02676089

Completed Disease control Sponsor: Chiesi Farmaceutici S.p.A. Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tested a new inhaler that combines three medicines (beclometasone, formoterol, and glycopyrronium) in people whose asthma was not well controlled with standard two-medication inhalers. Over 1,400 adults took part for 52 weeks. The triple inhaler improved lung function and reduced the number of moderate and severe asthma attacks compared to the two-medication inhaler alone.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

Beclometasone, formoterol, and glycopyrronium (triple-combination inhaler)

What this could lead to

If successful, this triple therapy could offer better asthma control for people whose symptoms persist despite standard dual inhalers.

What could go wrong

This is a completed Phase 3 trial, but results may not apply to all asthma patients. The triple inhaler may cause side effects like dry mouth or throat irritation.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

asthma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

ASTHMA

Contacts and locations

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Locations

Chiesi Clinical Trial Site 100701

Sofia, Bulgaria
Chiesi Clinical Trial Site 100702

Pleven, Bulgaria
Chiesi Clinical Trial Site 100703

Sofia, Bulgaria
Chiesi Clinical Trial Site 100704

Sofia, Bulgaria
Chiesi Clinical Trial Site 100705

Plovdiv, Bulgaria
Chiesi Clinical Trial Site 100706

Stara Zagora, Bulgaria
Chiesi Clinical Trial Site 100707

Blagoevgrad, Bulgaria
Chiesi Clinical Trial Site 100708

Plovdiv, Bulgaria
Chiesi Clinical Trial Site 100709

Sofia, Bulgaria
Chiesi Clinical Trial Site 100710

Varna, Bulgaria
Chiesi Clinical Trial Site 100711

Vidin, Bulgaria
Chiesi Clinical Trial Site 100712

Stara Zagora, Bulgaria
Chiesi Clinical Trial Site 100713

Haskovo, Bulgaria
Chiesi Clinical Trial Site 100715

Plovdiv, Bulgaria
Chiesi Clinical Trial Site 100716

Rousse, Bulgaria
Chiesi Clinical Trial Site 100718

Gabrovo, Bulgaria
Chiesi Clinical Trial Site 100719

Sofia, Bulgaria
Chiesi Clinical Trial Site 100720

Burgas, Bulgaria
Chiesi Clinical Trial Site 100721

Vidin, Bulgaria
Chiesi Clinical Trial Site 100722

Montana, Bulgaria
Chiesi Clinical Trial Site 112701

Minsk, Belarus
Chiesi Clinical Trial Site 112702

Minsk, Belarus
Chiesi Clinical Trial Site 112703

Homyel, Belarus
Chiesi Clinical Trial Site 112704

Homyel, Belarus
Chiesi Clinical Trial Site 112705

Minsk, Belarus
Chiesi Clinical Trial Site 203701

Prague, Czechia
Chiesi Clinical Trial Site 203702

Brandýs nad Labem, Czechia
Chiesi Clinical Trial Site 203703

Prague, Czechia
Chiesi Clinical Trial Site 203704

Opava, Czechia
Chiesi Clinical Trial Site 203705

Kralupy nad Vltavou, Czechia
Chiesi Clinical Trial Site 203706

Teplice, Czechia
Chiesi Clinical Trial Site 203707

Jindřichův Hradec, Czechia
Chiesi Clinical Trial Site 203708

Brno, Czechia
Chiesi Clinical Trial Site 203709

Miroslav, Czechia
Chiesi Clinical Trial Site 203710

Prague, Czechia
Chiesi Clinical Trial Site 203711

Blansko, Czechia
Chiesi Clinical Trial Site 203712

Varnsdorf, Czechia
Chiesi Clinical Trial Site 203713

Rokycany, Czechia
Chiesi Clinical Trial Site 276701

München, Germany
Chiesi Clinical Trial Site 276702

Leipzig, Germany
Chiesi Clinical Trial Site 276703

Hanover, Germany
Chiesi Clinical Trial Site 276704

Leipzig, Germany
Chiesi Clinical Trial Site 276705

Hamburg, Germany
Chiesi Clinical Trial Site 276707

Frankfurt am Main, Germany
Chiesi Clinical Trial Site 276708

Koblenz, Germany
Chiesi Clinical Trial Site 276709

Berlin, Germany
Chiesi Clinical Trial Site 276710

Leipzig, Germany
Chiesi Clinical Trial Site 276711

Bonn, Germany
Chiesi Clinical Trial Site 276712

Berlin, Germany
Chiesi Clinical Trial Site 276713

Münster, Germany
Chiesi Clinical Trial Site 276714

Frankfurt am Main, Germany
Chiesi Clinical Trial Site 276715

Mainz, Germany
Chiesi Clinical Trial Site 276716

Rosenheim, Germany
Chiesi Clinical Trial Site 348701

Szeged, Hungary
Chiesi Clinical Trial Site 348702

Siófok, Hungary
Chiesi Clinical Trial Site 348703

Monor, Hungary
Chiesi Clinical Trial Site 348704

Nyíregyháza, Hungary
Chiesi Clinical Trial Site 348705

Szombathely, Hungary
Chiesi Clinical Trial Site 348706

Szarvas, Hungary
Chiesi Clinical Trial Site 348707

Balassagyarmat, Hungary
Chiesi Clinical Trial Site 348708

Érd, Hungary
Chiesi Clinical Trial Site 348709

Létavértes, Hungary
Chiesi Clinical Trial Site 348710

Vásárosnamény, Hungary
Chiesi Clinical Trial Site 348712

Gödöllő, Hungary
Chiesi Clinical Trial Site 348713

Pécs, Hungary
Chiesi Clinical Trial Site 348714

Nyíregyháza, Hungary
Chiesi Clinical Trial Site 348715

Budapest, Hungary
Chiesi Clinical Trial Site 348717

Komárom, Hungary
Chiesi Clinical Trial Site 348718

Hatvan, Hungary
Chiesi Clinical Trial Site 348719

Mórahalom, Hungary
Chiesi Clinical Trial Site 348720

Pécs, Hungary
Chiesi Clinical Trial Site 348721

Debrecen, Hungary
Chiesi Clinical Trial Site 380701

Genova, Italy
Chiesi Clinical Trial Site 380702

Pavia, Italy
Chiesi Clinical Trial Site 380703

Catania, Italy
Chiesi Clinical Trial Site 380704

Bologna, Italy
Chiesi Clinical Trial Site 380705

Palermo, Italy
Chiesi Clinical Trial Site 380706

Tradate, Italy
Chiesi Clinical Trial Site 432701

Quilmes, Argentina
Chiesi Clinical Trial Site 432702

Buenos Aires, Argentina
Chiesi Clinical Trial Site 432703

San Miguel de Tucumán, Argentina
Chiesi Clinical Trial Site 432704

CABA, Argentina
Chiesi Clinical Trial Site 432705

Mar del Plata, Argentina
Chiesi Clinical Trial Site 432706

San Miguel de Tucumán, Argentina
Chiesi Clinical Trial Site 440701

Šiauliai, Lithuania
Chiesi Clinical Trial Site 440702

Vilnius, Lithuania
Chiesi Clinical Trial Site 440703

Vilnius, Lithuania
Chiesi Clinical Trial Site 440705

Vilnius, Lithuania
Chiesi Clinical Trial Site 616701

Warsaw, Poland
Chiesi Clinical Trial Site 616702

Bienkówka, Poland
Chiesi Clinical Trial Site 616703

Pabianice, Poland
Chiesi Clinical Trial Site 616704

Giżycko, Poland
Chiesi Clinical Trial Site 616705

Wroclaw, Poland
Chiesi Clinical Trial Site 616707

Lodz, Poland
Chiesi Clinical Trial Site 616708

Lodz, Poland
Chiesi Clinical Trial Site 616709

Poznan, Poland
Chiesi Clinical Trial Site 616710

Tarnów, Poland
Chiesi Clinical Trial Site 616711

Lodz, Poland
Chiesi Clinical Trial Site 616712

Świdnik, Poland
Chiesi Clinical Trial Site 616713

Bialystok, Poland
Chiesi Clinical Trial Site 616714

Wroclaw, Poland
Chiesi Clinical Trial Site 616715

Wroclaw, Poland
Chiesi Clinical Trial Site 616716

Grudziądz, Poland
Chiesi Clinical Trial Site 616717

Ostróda, Poland
Chiesi Clinical Trial Site 616718

Bialystok, Poland
Chiesi Clinical Trial Site 616719

Krakow, Poland
Chiesi Clinical Trial Site 616720

Proszowice, Poland
Chiesi Clinical Trial Site 616721

Skierniewice, Poland
Chiesi Clinical Trial Site 616722

Bielsko-Biala, Poland
Chiesi Clinical Trial Site 616723

Rzeszów, Poland
Chiesi Clinical Trial Site 616725

Katowice, Poland
Chiesi Clinical Trial Site 616726

Lodz, Poland
Chiesi Clinical Trial Site 616727

Bydgoszcz, Poland
Chiesi Clinical Trial Site 616728

Poznan, Poland
Chiesi Clinical Trial Site 616729

Katowice, Poland
Chiesi Clinical Trial Site 616730

Wilkowice, Poland
Chiesi Clinical Trial Site 616731

Otwock, Poland
Chiesi Clinical Trial Site 616732

Strzelce Opolskie, Poland
Chiesi Clinical Trial Site 616733

Mrozy, Poland
Chiesi Clinical Trial Site 616734

Krakow, Poland
Chiesi Clinical Trial Site 616735

Rzeszów, Poland
Chiesi Clinical Trial Site 616736

Krakow, Poland
Chiesi Clinical Trial Site 620702

Lisbon, Portugal
Chiesi Clinical Trial Site 620703

Figueira da Foz Municipality, Portugal
Chiesi Clinical Trial Site 620704

Aveiro, Portugal
Chiesi Clinical Trial Site 620707

Vila Nova de Gaia, Portugal
Chiesi Clinical Trial Site 620708

Loures, Portugal
Chiesi Clinical Trial Site 642703

Bucharest, Romania
Chiesi Clinical Trial Site 642704

Iași, Romania
Chiesi Clinical Trial Site 642705

Oradea, Romania
Chiesi Clinical Trial Site 642706

Brasov, Romania
Chiesi Clinical Trial Site 642707

Bucharest, Romania
Chiesi Clinical Trial Site 642708

Bucharest, Romania
Chiesi Clinical Trial Site 642709

Cluj-Napoca, Romania
Chiesi Clinical Trial Site 642710

Iași, Romania
Chiesi Clinical Trial Site 642711

Suceava, Romania
Chiesi Clinical Trial Site 642712

Craiova, Romania
Chiesi Clinical Trial Site 642713

Arad, Romania
Chiesi Clinical Trial Site 642714

Cluj-Napoca, Romania
Chiesi Clinical Trial Site 642715

Alexandru cel Bun, Romania
Chiesi Clinical Trial Site 642716

Cluj-Napoca, Romania
Chiesi Clinical Trial Site 642717

Bragadiru, Romania
Chiesi Clinical Trial Site 642718

Cluj-Napoca, Romania
Chiesi Clinical Trial Site 642719

Bucharest, Romania
Chiesi Clinical Trial Site 642721

Timișoara, Romania
Chiesi Clinical Trial Site 642722

Bacau, Romania
Chiesi Clinical Trial Site 642723

Bucharest, Romania
Chiesi Clinical Trial Site 642726

Cluj-Napoca, Romania
Chiesi Clinical Trial Site 643701

Ryazan, Russia
Chiesi Clinical Trial Site 643702

Moscow, Russia
Chiesi Clinical Trial Site 643703

Saratov, Russia
Chiesi Clinical Trial Site 643704

Kemerovo, Russia
Chiesi Clinical Trial Site 643705

Moscow, Russia
Chiesi Clinical Trial Site 643706

Moscow, Russia
Chiesi Clinical Trial Site 643707

Nizhny Novgorod, Russia
Chiesi Clinical Trial Site 643708

Vladikavkaz, Russia
Chiesi Clinical Trial Site 643709

Tomsk, Russia
Chiesi Clinical Trial Site 643710

Voronezh, Russia
Chiesi Clinical Trial Site 643711

Pyatigorsk, Russia
Chiesi Clinical Trial Site 643712

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643713

Kazan', Russia
Chiesi Clinical Trial Site 643714

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643715

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643716

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643717

Novosibirsk, Russia
Chiesi Clinical Trial Site 643718

Moscow, Russia
Chiesi Clinical Trial Site 643719

Kazan', Russia
Chiesi Clinical Trial Site 643720

Yaroslavl, Russia
Chiesi Clinical Trial Site 643721

Yekaterinburg, Russia
Chiesi Clinical Trial Site 643722

Moscow, Russia
Chiesi Clinical Trial Site 643723

Nizhny Novgorod, Russia
Chiesi Clinical Trial Site 643724

Odintsovo, Russia
Chiesi Clinical Trial Site 643725

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643726

Smolensk, Russia
Chiesi Clinical Trial Site 643727

Chelyabinsk, Russia
Chiesi Clinical Trial Site 643728

Tomsk, Russia
Chiesi Clinical Trial Site 643729

Orenburg, Russia
Chiesi Clinical Trial Site 643730

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643731

Kemerovo, Russia
Chiesi Clinical Trial Site 643732

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643733

Chelyabinsk, Russia
Chiesi Clinical Trial Site 643734

Yaroslavl, Russia
Chiesi Clinical Trial Site 643735

Moscow, Russia
Chiesi Clinical Trial Site 643736

Saratov, Russia
Chiesi Clinical Trial Site 643737

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643738

Vladimir, Russia
Chiesi Clinical Trial Site 643739

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643740

Stavropol, Russia
Chiesi Clinical Trial Site 643741

Kazan', Russia
Chiesi Clinical Trial Site 643742

Yaroslavl, Russia
Chiesi Clinical Trial Site 643743

Moscow, Russia
Chiesi Clinical Trial Site 643744

Nizhny Novgorod, Russia
Chiesi Clinical Trial Site 643745

Chelyabinsk, Russia
Chiesi Clinical Trial Site 643746

Kazan', Russia
Chiesi Clinical Trial Site 643749

Yaroslavl, Russia
Chiesi Clinical Trial Site 643752

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643754

Izhevsk, Russia
Chiesi Clinical Trial Site 643755

Ufa, Russia
Chiesi Clinical Trial Site 643757

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643758

Saint Petersburg, Russia
Chiesi Clinical Trial Site 643759

Tomsk, Russia
Chiesi Clinical Trial Site 703701

Nové Zámky, Slovakia
Chiesi Clinical Trial Site 703702

Ilava, Slovakia
Chiesi Clinical Trial Site 703703

Spišská Nová Ves, Slovakia
Chiesi Clinical Trial Site 703704

Bratislava, Slovakia
Chiesi Clinical Trial Site 703705

Košice, Slovakia
Chiesi Clinical Trial Site 703706

Košice, Slovakia
Chiesi Clinical Trial Site 703707

Bratislava, Slovakia
Chiesi Clinical Trial Site 703708

Štúrovo, Slovakia
Chiesi Clinical Trial Site 703709

Prievidza, Slovakia
Chiesi Clinical Trial Site 724701

Madrid, Spain
Chiesi Clinical Trial Site 724702

A Coruña, Spain
Chiesi Clinical Trial Site 724703

Badajoz, Spain
Chiesi Clinical Trial Site 724704

Madrid, Spain
Chiesi Clinical Trial Site 724705

Málaga, Spain
Chiesi Clinical Trial Site 724706

Badalona, Spain
Chiesi Clinical Trial Site 724707

Sabadell, Spain
Chiesi Clinical Trial Site 792701

Ankara, Turkey (Türkiye)
Chiesi Clinical Trial Site 792702

Ankara, Turkey (Türkiye)
Chiesi Clinical Trial Site 792703

Antalya, Turkey (Türkiye)
Chiesi Clinical Trial Site 792705

Maltepe, Turkey (Türkiye)
Chiesi Clinical Trial Site 792706

Kocaeli, Turkey (Türkiye)
Chiesi Clinical Trial Site 792707

Istanbul, Turkey (Türkiye)
Chiesi Clinical Trial Site 792708

Mersin, Turkey (Türkiye)
Chiesi Clinical Trial Site 792709

Yenişehir, Turkey (Türkiye)
Chiesi Clinical Trial Site 792710

Aydin, Turkey (Türkiye)
Chiesi Clinical Trial Site 804701

Dnipro, Ukraine
Chiesi Clinical Trial Site 804703

Vinnytsia, Ukraine
Chiesi Clinical Trial Site 804704

Zaporizhzhya, Ukraine
Chiesi Clinical Trial Site 804705

Kyiv, Ukraine
Chiesi Clinical Trial Site 804706

Vinnytsia, Ukraine
Chiesi Clinical Trial Site 804707

Vinnytsia, Ukraine
Chiesi Clinical Trial Site 804708

Zhytomyr, Ukraine
Chiesi Clinical Trial Site 804709

Kharkiv, Ukraine
Chiesi Clinical Trial Site 804710

Kherson, Ukraine
Chiesi Clinical Trial Site 804711

Ivano-Frankivsk, Ukraine
Chiesi Clinical Trial Site 804712

Lviv, Ukraine
Chiesi Clinical Trial Site 804713

Kiev, Ukraine
Chiesi Clinical Trial Site 804714

Vinnytsia, Ukraine
Chiesi Clinical Trial Site 804715

Sumy, Ukraine
Chiesi Clinical Trial Site 826701

Soham, United Kingdom
Chiesi Clinical Trial Site 826702

Llanelli, United Kingdom
Chiesi Clinical Trial Site 826703

London, United Kingdom
Chiesi Clinical Trial Site 826704

Manchester, United Kingdom