Could a 'Use-When-Needed' inhaler help teens with asthma?

NCT ID NCT05689983

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study tests whether a symptom-driven inhaler (budesonide/formoterol) works better for teens with asthma who often forget their daily maintenance inhalers. Researchers will compare adherence and asthma flare-ups between the standard daily inhaler plus rescue inhaler group and the symptom-driven group. The goal is to find a simpler approach that reduces hospitalizations and improves asthma control.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
budesonide/formoterol combination (Symbicort)
What this could lead to
If this approach works, it could offer a simpler, more effective way for teens to manage asthma without needing to remember daily inhalers.
What could go wrong
This is a small early-phase study with only 40 participants, so results may not apply to everyone. The symptom-driven strategy might not control asthma as well as daily maintenance therapy in some patients.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Washington University in St. Louis School of Medicine

    St Louis, Missouri, 63110, United States

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