Skin test may personalize asthma care for kids
NCT ID NCT04699604
First seen Jun 27, 2026 · Last updated Jul 01, 2026 · Updated 1 time
Summary
This study tests whether a skin test that measures histamine response can help doctors decide if adding an antihistamine (Levocetirizine) to standard asthma treatment improves control in children aged 6-17 with allergic asthma. About 300 African American/Black and Caucasian/White children will be randomly assigned to receive either the antihistamine or a placebo for 6 weeks, then switch. The goal is to see if the skin test predicts who benefits most from antihistamine therapy.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
Levocetirizine (Xyzal)
What this could lead to
If successful, this could provide a simple skin test to identify which children with allergic asthma would benefit from adding an antihistamine to their current treatment.
What could go wrong
This is a Phase 3 trial, but it is still testing a biomarker approach. The antihistamine may not improve asthma control for all children, and results may vary by race or phenotype.
Disclaimer
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This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Locations
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Children's Mercy Hospital
Kansas City, Missouri, 64108, United States