Brain infusion trial hopes to restore movement in chronic stroke patients
NCT ID NCT07318714
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tests a new drug called ASP2246 for adults who have trouble moving after a stroke. In the first part, small groups get increasing doses via brain surgery to check safety. In the second part, some get the drug and others get a sham surgery, with neither patient nor doctor knowing who got what. All participants then do physical therapy for 12 weeks and are followed for a year.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
ASP2246
What this could lead to
If successful, this could point toward a new treatment to improve movement after a stroke.
What could go wrong
This is a very early first-in-human trial with only 84 participants. The brain surgery carries risks like bleeding or infection, and the treatment may not improve function.
Disclaimer
Read more
Show less
This is a summary of
the original study
.
Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
Get updates
Get notified about this study
Sign up to get updates when this study changes or when new studies for CHRONIC ISCHEMIC STROKE are added.
By submitting, you agree to our Terms of use
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Show contact details
Enter your email to view the contact information for this study.
By submitting, you agree to our Terms of use
Study contacts
-
Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
-
Kyoto University Hospital
RECRUITINGKyoto, Japan
-
Toyama University Hospital
RECRUITINGToyama, Toyama, Japan