New drug ARX517 targets advanced prostate cancer in early trial

NCT ID NCT04662580

First seen Nov 01, 2025 · Last updated May 06, 2026 · Updated 22 times

Summary

This early-phase study tests a new drug called ARX517, alone or with other prostate cancer treatments, in 183 men with metastatic prostate cancer that has spread. The main goal is to check the drug's safety and find the right dose. Participants must have confirmed prostate cancer and, if not surgically castrated, must continue hormone therapy during the study.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Locations

  • Carolina Urologic Research Center

    Myrtle Beach, South Carolina, 29572, United States

  • GU Research Network

    Omaha, Nebraska, 68130, United States

  • Indiana University Melvin and Bren Simon Cancer Center

    Indianapolis, Indiana, 46202-5116, United States

  • UC San Diego Moores Cancer Center

    La Jolla, California, 92093, United States

  • UCSF Medical Center at Mission Bay

    San Francisco, California, 94143-2350, United States

  • University Hospitals Cleveland Medical Center

    Cleveland, Ohio, 44106, United States

  • University of California, Los Angeles School of Medicine

    Los Angeles, California, 90095-3000, United States

  • University of Michigan Comprehensive Cancer Center

    Ann Arbor, Michigan, 48109-5000, United States

  • University of Washington

    Seattle, Washington, 98101, United States

  • Washington University St. Louis School Medicine Siteman Cancer Center

    St Louis, Missouri, 63110, United States

  • Weill Cornell Medical College

    New York, New York, 10021-5663, United States

  • Winship Cancer Institute of Emory University

    Atlanta, Georgia, 30322, United States

Conditions

Explore the condition pages connected to this study.