Eye drops may shield tear ducts from radioactive iodine damage
NCT ID NCT05999630
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This phase 3 trial tests whether using artificial tears after radioactive iodine therapy can prevent tear duct blockage in thyroid cancer patients. Radioactive iodine can collect in tears and damage tear ducts, leading to blockage. 100 adults receiving high-dose radioactive iodine will use artificial tears or standard care, and their tear ducts will be checked for blockage over two years.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
artificial tears (methylcellulose)
What this could lead to
If it works, this could provide a simple, low-cost way to prevent a common side effect of radioactive iodine therapy for thyroid cancer.
What could go wrong
This is a relatively small phase 3 trial, and the benefit may be modest or not statistically significant. The artificial tears must be used exactly as directed, and some patients may still develop tear duct blockage.
Disclaimer
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Contact Phone: •••-•••-•••• Email: •••••@•••••