Sweeteners under scrutiny: could aspartame or sucralose worsen prediabetes?
NCT ID NCT05337098
First seen Dec 11, 2025 · Last updated Jun 23, 2026 · Updated 29 times
Summary
This study looks at whether the artificial sweeteners aspartame and sucralose change how the body handles sugar in older adults with prediabetes. Researchers will give participants either one of the sweeteners or a placebo for several weeks and track blood sugar levels continuously. The goal is to see if these common sweeteners might actually make blood sugar control worse.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Virginia Tech
RECRUITINGBlacksburg, Virginia, 24061, United States
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What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
aspartame and sucralose (artificial sweeteners)
What this could lead to
If it works, this could help people with prediabetes choose which artificial sweeteners are safer for blood sugar control.
What could go wrong
This is a small, early-stage study with only 30 participants. Results may not apply to everyone, and the sweeteners might not affect blood sugar as expected.
Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.