New combo shows promise for High-Risk leukemia patients

NCT ID NCT02688140

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This study tested a new treatment for adults with a high-risk form of acute promyelocytic leukemia (APL). The experimental therapy combined arsenic trioxide, ATRA, and a low dose of idarubicin, aiming to improve survival and reduce side effects compared to the standard chemotherapy regimen. The trial enrolled 133 patients across Europe to see if this approach leads to better outcomes and quality of life.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • AML-CG study group

    All Participating Sites, Germany

  • AML-SG study group

    All Participating Sites, Germany

  • French-Belgian-Swiss APL study group

    All Participating Sites, France

  • GIMEMA study group

    All Participating Sites, Italy

  • HOVON study group

    All Participating Sites, Netherlands

  • OSHO study group

    All Participating Sites, Germany

  • PETHEMA study group

    All Participating Sites, Spain

  • SAL study group

    All Participating Sites, Germany

More trials for these conditions

Other studies related to the condition(s) this trial covers.