Leukemia treatment showdown: which works best?
NCT ID NCT02938858
First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This registry study follows 400 patients with a specific type of leukemia (non-high-risk APL) who are 70 or younger. It compares two standard treatments: ATRA plus chemotherapy versus ATRA plus arsenic trioxide. The goal is to see which approach leads to better long-term outcomes and fewer side effects, helping doctors make informed treatment decisions.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- ATRA plus chemotherapy or ATRA plus arsenic trioxide (ATO)
- What this could lead to
- If successful, this registry could help doctors choose the best first-line treatment for non-high-risk APL, improving survival and reducing side effects.
- What could go wrong
- This is an observational registry, not a controlled trial, so results may be influenced by treatment choices. It does not test a new drug, so no direct breakthrough is expected.
This is an AI summary of the original study and may miss details. Read our disclaimer.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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CH Dr Schaffner
Lens, 62307, France
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CHR Metz-Thionville - Hôpital de Marcy
Metz, 57085, France
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CHRU de Brest - Pédiatrie Spécialisée
Brest, 29609, France
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CHU Bordeaux Pellegrin enfant
Bordeaux, 33076, France
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CHU Estaing
Clermont-Ferrand, 63100, France
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CHU Hôpital Sud - service Hémato-oncologie Pédiatrique
Rennes, 35203, France
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CHU Hôtel Dieu
Nantes, 44035, France
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CHU Saint Eloi
Montpellier, 34095, France
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CHU de Grenoble
Grenoble, 38043, France
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Centre Henri Becquerel
Rouen, 76038, France
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Centre Hospitalier V. Dupouy
Argenteuil, 95107, France
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Centre Hospitalier d'Aix en Provence
Aix-en-Provence, 13616, France
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Chru - Hopital Claude Huriez
Lille, 59037, France
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Chu Timone
Marseille, 13385, France
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Groupe Hospitalier SUD
Amiens, 80054, France
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Hopital Andre Mignot
Le Chesnay, 78150, France
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Hôpital Henri Mondor
Créteil, 94100, France
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Hôpital Jean Minjoz
Besançon, 25030, France
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Hôpital Necker
Paris, 75015, France
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Hôpital Robert Debré
Paris, 75019, France
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Hôpital TROUSSEAU
Paris, 75012, France
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Hôpital V. Provo
Roubaix, 59056, France
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Hôpital de la Source
Orléans, 45100, France
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Hôpital universitaire Dupuytren
Limoges, 87042, France
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IUCT Oncopole
Toulouse, 31059, France
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Institut Paoli Calmettes
Marseille, 13273, France
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Institut de Cancerologie de La Loire
Saint-Priest-en-Jarez, 42270, France
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