Leukemia treatment showdown: which First-Line therapy works best?

NCT ID NCT02938858

First seen Jan 03, 2026 · Last updated Apr 30, 2026 · Updated 18 times

Summary

This study is a registry that tracks 400 adults aged 70 or younger with a specific, less aggressive form of acute promyelocytic leukemia (APL). It compares two standard first-line treatments—ATRA plus chemotherapy versus ATRA plus arsenic trioxide—to see which is more effective and has fewer side effects. The goal is to gather real-world data to help doctors choose the best approach for each patient.

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Contacts and locations

Locations

  • CH Dr Schaffner

    Lens, 62307, France

  • CHR Metz-Thionville - Hôpital de Marcy

    Metz, 57085, France

  • CHRU de Brest - Pédiatrie Spécialisée

    Brest, 29609, France

  • CHU Bordeaux Pellegrin enfant

    Bordeaux, 33076, France

  • CHU Estaing

    Clermont-Ferrand, 63100, France

  • CHU Hôpital Sud - service Hémato-oncologie Pédiatrique

    Rennes, 35203, France

  • CHU Hôtel Dieu

    Nantes, 44035, France

  • CHU Saint Eloi

    Montpellier, 34095, France

  • CHU de Grenoble

    Grenoble, 38043, France

  • Centre Henri Becquerel

    Rouen, 76038, France

  • Centre Hospitalier V. Dupouy

    Argenteuil, 95107, France

  • Centre Hospitalier d'Aix en Provence

    Aix-en-Provence, 13616, France

  • Chru - Hopital Claude Huriez

    Lille, 59037, France

  • Chu Timone

    Marseille, 13385, France

  • Groupe Hospitalier SUD

    Amiens, 80054, France

  • Hopital Andre Mignot

    Le Chesnay, 78150, France

  • Hôpital Henri Mondor

    Créteil, 94100, France

  • Hôpital Jean Minjoz

    Besançon, 25030, France

  • Hôpital Necker

    Paris, 75015, France

  • Hôpital Robert Debré

    Paris, 75019, France

  • Hôpital TROUSSEAU

    Paris, 75012, France

  • Hôpital V. Provo

    Roubaix, 59056, France

  • Hôpital de la Source

    Orléans, 45100, France

  • Hôpital universitaire Dupuytren

    Limoges, 87042, France

  • IUCT Oncopole

    Toulouse, 31059, France

  • Institut Paoli Calmettes

    Marseille, 13273, France

  • Institut de Cancerologie de La Loire

    Saint-Priest-en-Jarez, 42270, France

Conditions

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