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Can a berry extract shield Athletes' immune systems after intense exercise?

NCT ID NCT07829523

NEW Knowledge-focused Sponsor: Hanna Dziewiecka Source: ClinicalTrials.gov ↗

What the study statuses mean

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Recruitment status, easiest to join first

Recruiting now
This trial is taking on new participants right now.
Not yet recruiting This study
Registered, but not yet taking participants.
By invitation only
Not open to general applications. Only people the study team invites can take part.
Paused
Paused for now. It may or may not start again.
Ongoing
Running, but no longer taking on new participants.
Completed
The trial has finished. Results may not be published yet.
Stopped early
Stopped early, before it reached the end. That can be for many reasons, including safety.
Cancelled
Cancelled before anyone took part.

Expanded access (not trials)

Expanded access
Not a trial. This treatment can be requested outside a study, case by case, for people who qualify.
Expanded access (paused)
Not a trial. The treatment can normally be requested outside a study, but is unavailable right now.
Expanded access (ended)
Not a trial. The treatment could once be requested outside a study, but no longer can.
Approved
The treatment has been approved, so it is available normally rather than through this programme.

When the status isn't known

Details not published
The full record has not been published yet, so there is little to show here.
Status unknown
This status has not been confirmed recently, so it may be out of date.

First seen Sep 21, 2026 · Last updated Sep 21, 2026

Summary

Researchers are testing whether an 8-week course of aronia berry extract changes how the immune system and gut respond to high-intensity exercise in trained male football players. Forty participants receive either the extract or a placebo, and blood samples are taken before, right after, and one hour after exercise testing. The study measures markers of gut leakage and immune cell activation to see if the supplement makes a difference.

What this could mean

Our plain-language read of the trial. This is informational only, not medical advice or a prediction.

Active substance
Aronia melanocarpa (chokeberry) extract capsules
What this could lead to
If aronia extract blunts the immune and gut-leakage response to hard training, it could point toward a simple dietary supplement that helps athletes recover and stay healthy during intense exercise.
What could go wrong
This is a small, 40-person study in healthy young male football players, so any effect may be modest and may not apply to other athletes, women, or older adults. Supplements often fail to show a benefit over placebo in controlled trials.

This is an AI summary of the original study and may miss details. Read our disclaimer.

Study facts

What this study's own registry entry says, in plain language.

Phase

Not a phased trial

Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.

Participants

About 40 people

The number the study aims to enrol. It can still change while the study runs.

Expected to start

Oct 2026

An estimate. Start dates often move.

Expected to finish

Nov 2026

An estimate. End dates often move.

Lead sponsor

Other sponsor

The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.

Who can take part

This study's own entry requirements. Only the study team can say for certain whether you qualify.

Ages

16 to 35 years

Sex

Male participants only

Healthy volunteers

Accepted

You do not need to have the condition being studied to take part.

Show the full entry requirements

Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.

Inclusion Criteria: * Male participants aged 16-35 years. * Regularly training football players. * Healthy and medically eligible to participate in the exercise testing. * Willingness to comply with the study procedures and pre-test instructions. Exclusion Criteria: * Use of antibiotics, metformin, probiotics, prebiotics, or synbiotics within the 3 months preceding enrollment. * Vegan diet. * Regular gut-training practices. * Gastrointestinal infection. * Other significant diseases that, in the opinion of the study physician, may affect eligibility for participation.

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Conditions

The condition(s) this trial relates to.

Motor Activity

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Exercise training

How to take part

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