New combo therapy aims to tackle Hard-to-Treat myeloma

NCT ID NCT06121843

Recruiting now Disease control Sponsor: Juno Therapeutics, Inc., a Bristol-Myers Squibb Company Source: ClinicalTrials.gov ↗

First seen Jun 27, 2026 · Last updated Jul 17, 2026 · Updated 2 times

Summary

This early-stage study is testing a new cell therapy (arlocabtagene autoleucel) combined with other drugs in people with multiple myeloma that has come back or stopped responding to treatment. The main goal is to find safe doses and check for side effects. About 147 adults will take part to see if these combinations can help control the disease.

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Conditions

The condition(s) this trial relates to.

plasma cell myeloma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

MULTIPLE MYELOMA

Contacts and locations

Locations

Arthur J.E. Child Comprehensive Cancer Centre
RECRUITING

Calgary, Alberta, T2N 5G2, Canada
Beth Israel Deaconess Medical Center
RECRUITING

Boston, Massachusetts, 02215, United States
City of Hope Comprehensive Cancer Center
RECRUITING

Duarte, California, 91010, United States
Dana-Farber Cancer Institute
RECRUITING

Boston, Massachusetts, 02215, United States
John Theurer Cancer Center at Hackensack University Medical Center
RECRUITING

Hackensack, New Jersey, 07601-2191, United States
Laura and Isaac Perlmutter Cancer Center
RECRUITING

New York, New York, 10016, United States
Local Institution - 0009
COMPLETED

New York, New York, 10032, United States
Local Institution - 0023
WITHDRAWN

Pittsburgh, Pennsylvania, 15232, United States
Mayo Clinic in Arizona - Phoenix
RECRUITING

Phoenix, Arizona, 85054, United States
Mayo Clinic in Florida
RECRUITING

Jacksonville, Florida, 32224, United States
Mayo Clinic in Rochester, Minnesota
RECRUITING

Rochester, Minnesota, 55905, United States
Memorial Sloan Kettering Cancer Center
RECRUITING

New York, New York, 10065, United States
Northside Hospital
RECRUITING

Atlanta, Georgia, 30342, United States
Princess Margaret Cancer Centre
RECRUITING

Toronto, Ontario, M5G 2M9, Canada
Roswell Park Cancer Institute
RECRUITING

Buffalo, New York, 14263, United States
Tennessee Oncology
RECRUITING

Nashville, Tennessee, 37203, United States
University Of Nebraska Medical Center
RECRUITING

Omaha, Nebraska, 68198, United States
University of Alabama at Birmingham
RECRUITING

Birmingham, Alabama, 35294-3300, United States
University of Texas MD Anderson Cancer Center
RECRUITING

Houston, Texas, 77030, United States

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