New mRNA drug hopes to help cystic fibrosis patients who Can't use current therapies
NCT ID NCT06747858
First seen Nov 01, 2025 · Last updated Jun 12, 2026 · Updated 28 times
Summary
This study tests an experimental mRNA medicine called ARCT-032 in 33 adults with cystic fibrosis who cannot take or do not benefit from current CFTR modulators. The goal is to see if the drug is safe and can improve lung function and quality of life. Participants will receive multiple doses, and researchers will monitor side effects and measure changes in breathing tests.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Boston Children's Hospital
RECRUITINGBoston, Massachusetts, 02115, United States
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Children's Hospital of Los Angeles
RECRUITINGLos Angeles, California, 90027, United States
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Children's National Hospital
NOT_YET_RECRUITINGWashington D.C., District of Columbia, 20010, United States
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Cleveland Clinic Foundation
RECRUITINGCleveland, Ohio, 44195, United States
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Joe DiMaggio Children's Hospital
RECRUITINGHollywood, Florida, 33021, United States
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Medical University of South Carolina
RECRUITINGCharleston, South Carolina, 29425, United States
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Seattle Children's Hospital
RECRUITINGSeattle, Washington, 98105, United States
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The Cystic Fibrosis Institute
ACTIVE_NOT_RECRUITINGNorthfield, Illinois, 60093, United States
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UT Health San Antonio
RECRUITINGSan Antonio, Texas, 78229, United States
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University of Arizona
RECRUITINGTucson, Arizona, 85724, United States
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University of Arkansas for Medical Sciences
RECRUITINGLittle Rock, Arkansas, 72205, United States
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Vanderbilt University Medical Center
RECRUITINGNashville, Tennessee, 37232, United States
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Washington University School of Medicine
RECRUITINGSt Louis, Missouri, 63144, United States
Conditions
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