New airway implant aims to free trapped air in emphysema patients

NCT ID NCT06891755

First seen Nov 01, 2025 · Last updated May 03, 2026 · Updated 20 times

Summary

This study tests a permanent implant called the Apreo BREATHE system, which props open airways to release trapped air in the lungs of people with COPD and emphysema. The goal is to improve breathing and quality of life. Up to 250 adults aged 40-84 who still have shortness of breath despite standard treatments will be followed for 3 years to check safety and effectiveness.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

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Locations

  • Banner Health

    RECRUITING

    Gilbert, Arizona, 85234, United States

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  • Beth Israel Deaconess Medical Center

    RECRUITING

    Boston, Massachusetts, 02215, United States

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  • Cleveland Clinic Foundation

    RECRUITING

    Cleveland, Ohio, 44103, United States

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  • Clinical Research Associates of Central Pennsylvania

    RECRUITING

    DuBois, Pennsylvania, 15801, United States

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  • Houston Methodist/Primary Critical Care

    RECRUITING

    Houston, Texas, 77030, United States

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  • Inova Health Care Services

    RECRUITING

    Falls Church, Virginia, 22042, United States

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  • Karl Landsteiner Institute - Klink Floridsdorf

    RECRUITING

    Vienna, A-1210, Austria

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  • Mayo Clinic

    RECRUITING

    Jacksonville, Florida, 32224, United States

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  • Medical College of Wisconsin

    RECRUITING

    Milwaukee, Wisconsin, 53226, United States

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  • OSF St Francis Medical Center

    RECRUITING

    Peoria, Illinois, 61637, United States

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  • Orlando Health

    RECRUITING

    Orlando, Florida, 32806, United States

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  • Royal Brompton Hospital

    RECRUITING

    London, SW36JY, United Kingdom

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  • St. Bartholomew's Hospital

    RECRUITING

    London, EC1A 7BE, United Kingdom

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  • Temple University

    RECRUITING

    Philadelphia, Pennsylvania, 19140, United States

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  • The Ohio State University

    RECRUITING

    Columbus, Ohio, 43210, United States

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  • University Medical Center Groningen

    RECRUITING

    Groningen, 9713 GZ, Netherlands

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  • University of Alabama at Birmingham

    RECRUITING

    Birmingham, Alabama, 35233, United States

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  • University of California at Davis

    RECRUITING

    Sacramento, California, 95817, United States

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  • University of Chicago

    RECRUITING

    Chicago, Illinois, 60637, United States

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  • University of Kansas Medical Center Research Institute

    RECRUITING

    Kansas City, Kansas, 66160, United States

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  • University of Michigan

    RECRUITING

    Ann Arbor, Michigan, 48109, United States

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  • University of Pittsburgh Medical Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15213, United States

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Conditions

Explore the condition pages connected to this study.