Optimizing low-dose contrast media protocol for Low-kVp abdominopelvic CT in suspected acute appendicitis
NCT ID NCT05878665
First seen Sep 09, 2026 ยท Last updated Sep 09, 2026
Summary
The purpose of this clinical study is to test the performance of low radiation dose abdominal CT combined with low dose contrast media for the diagnosis of acute appendicitis in young patients. The main questions to be answered are: 1. Can low-dose contrast media paired with low-dose radiation CT of the abdomen provide acceptable diagnostic accuracy in acute appendicitis? 2. How much radiation dose can be saved by using low radiation dose abdominal CT in combination with low dose contrast media?
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Study facts
What this study's own registry entry says, in plain language.
- Phase
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Not a phased trial
Phase numbers describe drug development. The registry uses this when they do not apply, as it does for trials of devices, procedures or behaviour changes, and for observational studies.
- Participants
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109 people
The number who actually took part.
- Started
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Dec 2023
- Finished
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Sep 2026
- Lead sponsor
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Other sponsor
The registry's catch-all category, for sponsors it does not file as a company, a government agency, or a research network.
Who can take part
This study's own entry requirements. Only the study team can say for certain whether you qualify.
- Ages
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19 to 44 years
- Sex
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Anyone
- Healthy volunteers
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Not accepted
This study is not open to healthy volunteers. The entry requirements below say who it is open to.
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Copied word for word from the study's registry entry, so the wording is the study team's rather than ours.
Inclusion criteria: * Patients in the emergency department with suspected acute appendicitis based on clinical examination * Patients scheduled for contrast-enhanced CT of the abdomen and pelvis for diagnosis of suspected acute appendicitis. Exclusion criteria: * Patients who decline to participate * Contraindications to contrast-enhanced CT (eGFR \< 30 mL/min/173 m\^2 or pregnant) * BMI \>= 30.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Seoul St. Mary's Hospital
Seoul, 06591, South Korea
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Other studies related to the condition(s) this trial covers.
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