Could a simple pill replace daily shots for clot prevention after cancer surgery?

NCT ID NCT07189897

First seen Jun 26, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study tests whether apixaban (a pill taken twice a day) is a safe and more satisfying alternative to enoxaparin (a daily shot) for preventing blood clots after head and neck cancer surgery. About 76 adults will take one of the two medicines for 10 days after surgery. Researchers will track side effects, patient satisfaction, and how well participants stick to the treatment plan.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

apixaban (pill) and enoxaparin (shot)

What this could lead to

If successful, this could show that a simple pill is a safe and more convenient alternative to daily shots for preventing blood clots after head and neck cancer surgery.

What could go wrong

This is a small pilot study (76 people), so results may not apply to everyone. It compares two existing drugs, not a new breakthrough, and side effects are possible with both.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

head and neck cancer Head and Neck Neoplasms thrombotic disease venous thromboembolism prevention target

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • SUNY Upstate

    RECRUITING

    Syracuse, New York, 13210, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••