Can we predict apixaban levels in asian hearts?

NCT ID NCT07747948

First seen Aug 05, 2026 · Last updated Aug 06, 2026 · Updated 1 time

Summary

This observational study looks at how the blood thinner apixaban is processed in the bodies of Asian patients with atrial fibrillation. Researchers will analyze existing medical records and blood concentration data from about 200 patients to understand how factors like kidney function and body weight affect drug levels. The goal is to identify what influences apixaban clearance and distribution, which could help personalize dosing in the future.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance
Apixaban (oral tablet, 2.5 mg or 5 mg twice daily)
What this could lead to
If successful, this could help doctors tailor apixaban dosing for Asian patients with atrial fibrillation, potentially improving safety and effectiveness.
What could go wrong
This is an observational study using existing data, so it cannot prove cause and effect. Results may not apply to all patients, and the analysis depends on the quality of the collected records.

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Conditions

The condition(s) this trial relates to.

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Faculty of Medicine, Chulalongkorn University

    Pathum Wan, Bangkok, 10330, Thailand