New Mouth-Dissolving treatment tested for aggressive brain cancer recurrence
NCT ID NCT06011109
First seen Nov 01, 2025 · Last updated Apr 06, 2026 · Updated 30 times
Summary
This study is testing whether adding a new experimental medicine called APG-157, taken as dissolving pastilles in the mouth, can improve outcomes for people whose high-grade glioma (a type of aggressive brain tumor) has returned after previous treatment. Participants will take the APG-157 pastilles three times daily while continuing their standard bevacizumab infusions. The main goals are to see if this combination helps slow tumor growth, extends life, and improves quality of life for up to 30 adults with this condition.
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Study contacts
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Contact
Email: •••••@•••••
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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Mayo Clinic
RECRUITINGRochester, Minnesota, 55905, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
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University of Nebraska Medical Center
RECRUITINGOmaha, Nebraska, 68198, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••
Conditions
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