New triple-drug attack aims to outsmart resistant prostate cancer

NCT ID NCT06059118

First seen Jan 14, 2026 · Last updated May 12, 2026 · Updated 20 times

Summary

This study tests a sequence of three drugs—DFMO, high-dose testosterone, and enzalutamide—in 50 men with metastatic prostate cancer that has stopped responding to standard hormone therapy. The goal is to see if this approach can lower PSA levels and delay cancer growth. Participants must have no pain from their cancer and have already tried abiraterone.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • Johns Hopkins University: Sidney Kimmel Comprehensive Cancer Center

    RECRUITING

    Baltimore, Maryland, 21287, United States

    Contact Phone: •••-•••-•••• Email: •••••@•••••

    Contact

Conditions

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