New cocktail of four drugs tested for tough prostate cancer

NCT ID NCT02913196

First seen May 08, 2026 · Last updated Jun 16, 2026 · Updated 11 times

Summary

This early-phase trial tested a combination of four drugs (apalutamide, abiraterone, docetaxel, and prednisone) in 16 men with metastatic castrate-resistant prostate cancer that had stopped responding to hormone therapy. The main goal was to find a safe dose of apalutamide when used with the other drugs. Researchers also tracked PSA levels and tumor changes to see if the combination could help control the disease.

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Contacts and locations

Locations

  • GU Research Network/Urology Cancer Center

    Omaha, Nebraska, 68130, United States

  • Weill Cornell Medical College

    New York, New York, 10065, United States

Conditions

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