New study to see if antivirals help immunocompromised COVID patients

NCT ID NCT06683937

Not yet recruiting Knowledge-focused Sponsor: Assistance Publique - Hôpitaux de Paris Source: ClinicalTrials.gov ↗

First seen Jun 26, 2026 · Last updated Jun 26, 2026

Summary

This study will review medical records of 300 immunocompromised adults hospitalized with COVID-19 in France between June 2023 and April 2024. Researchers want to see how well antiviral drugs like nirmatrelvir/ritonavir and remdesivir work in these patients. The goal is to track their recovery and any side effects.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance: nirmatrelvir/ritonavir or remdesivir
What this could lead to: If successful, this could help doctors understand which antiviral treatments work best for immunocompromised patients with COVID-19.
What could go wrong: This is an observational study that only looks back at medical records, so it cannot prove cause and effect. Results may not apply to all patients.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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Conditions

The condition(s) this trial relates to.

COVID-19

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

IMMUNOCOMPROMISED PATIENTS SARS-COV-2 DISEASE

Contacts and locations

Locations

CH Périgueux

Périgueux, 24000, France
CHD Vendée (La Roche sur Yon)

La Roche-sur-Yon, 85000, France
CHRU Lille

Lille, 59000, France
CHU Angers

Angers, 49000, France
CHU Caen

Caen, 14000, France
CHU Nantes

Nantes, 44000, France
CHU Nord Marseille

Marseille, 13000, France
CHU Nîmes Caremeau

Nîmes, 30000, France
CHU Poitiers

Poitiers, 86000, France
CHU Reims

Reims, 51100, France
CHU Sud Réunion

Saint-Pierre, 97410, France
CHU Toulouse

Toulouse, 31000, France
Hôpital Bichat

Paris, 75018, France
Hôpital Necker-Enfants Malades

Paris, 75015, France
Hôpital Pasteur, Colmar

Colmar, 68000, France
Hôpital Saint-Louis

Paris, 75010, France

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