Blood test before heart surgery may predict clotting risk

NCT ID NCT07549568

Not yet recruiting Knowledge-focused Sponsor: Sahlgrenska University Hospital Source: ClinicalTrials.gov ↗

First seen Jun 24, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether measuring antithrombin levels in the blood before heart surgery can predict if a patient will respond poorly to heparin, a blood thinner used during surgery. Researchers will collect one extra blood sample from 300 adults undergoing planned heart surgery with a heart-lung machine. No changes are made to standard care. The goal is to find a threshold that helps doctors spot heparin resistance early, potentially improving safety and reducing unnecessary treatments.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

What this could lead to: If successful, this could help doctors identify patients at risk of heparin resistance before heart surgery, leading to safer and more personalized treatment.
What could go wrong: This is an observational study, not a treatment trial. It may not find a clear threshold, and results may not change practice without further research.

This is an AI summary of the original study and may miss details. Read our disclaimer.

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As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

CARDIAC SURGERY CARDIOPULMONARY BYPASS HEPARIN RESISTANCE

Contacts and locations

Locations

Sahlgrenska University Hospital

Gothenburg, Västra Götalandsregionen, 41345, Sweden

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