Antioxidant cocktail may shield seniors from bed rest damage

NCT ID NCT04351113

First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time

Summary

This study looks at whether antioxidant supplements can prevent muscle loss and blood vessel problems in older adults (ages 65-85) during five days of bed rest. Participants take either a placebo or two antioxidants (MITO-AO and PB-125) while researchers measure changes in blood flow and muscle function. The goal is to understand how inactivity harms the body and find ways to protect it.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

MITO-AO and PB-125 (dietary supplements)

What this could lead to

If successful, this could point toward a simple supplement strategy to protect older adults from muscle loss and blood vessel problems during hospital stays or bed rest.

What could go wrong

This is an early-stage study with only 82 participants, so results may not apply to everyone. The supplements may not work as hoped, and the study focuses on short-term bed rest, not long-term inactivity.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

muscular atrophy skeletal muscle disorder

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • VA Medical Center

    Salt Lake City, Utah, 84148, United States