Do we really need antibiotics after bladder removal? new trial investigates
NCT ID NCT06190197
First seen Jun 25, 2026 · Last updated Jun 27, 2026 · Updated 1 time
Summary
This study looks at whether it is safe to skip preventive antibiotics after bladder removal surgery for muscle-invasive bladder cancer. Half of the 120 participants will take nitrofurantoin daily for 10–21 days after surgery, while the other half will receive no antibiotics. The goal is to compare rates of urinary tract infections in the first 90 days after surgery.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
Active substance
nitrofurantoin
What this could lead to
If successful, this could show that not all patients need antibiotics after bladder removal surgery, reducing unnecessary drug use and side effects.
What could go wrong
This is a very early-phase trial with only 120 people, so results may not apply broadly. The study focuses on infection rates, not long-term outcomes or survival.
Disclaimer
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This is a summary of
the original study
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Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
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Study contacts
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Contact
Phone: •••-•••-•••• Email: •••••@•••••
Locations
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University of Minnesota
RECRUITINGMinneapolis, Minnesota, 55414, United States
Contact Phone: •••-•••-•••• Email: •••••@•••••