Could antibiotics tame sarcoidosis? new study targets hidden bacteria

NCT ID NCT05291468

First seen Feb 16, 2026 · Last updated May 01, 2026 · Updated 9 times

Summary

This study tests whether a combination of two antibiotics (azithromycin and doxycycline) can reduce bacteria found in the tissue of some sarcoidosis patients and lower inflammation. About 40 adults with biopsy-confirmed sarcoidosis and active inflammation on a PET scan will receive the antibiotics or placebo. The goal is to see if targeting the bacteria improves disease activity and quality of life.

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Contacts and locations

Locations

  • St. Antonius Hospital

    Nieuwegein, Utrecht, 3435 CM, Netherlands

Conditions

Explore the condition pages connected to this study.