Can a blood gel with antibiotics speed wisdom tooth healing?
NCT ID NCT07764757
First seen Aug 14, 2026 · Last updated Aug 14, 2026
Summary
This trial tests whether adding an antibiotic to a blood-derived gel (platelet-rich fibrin) placed in the socket after wisdom tooth removal improves recovery. It compares the antibiotic-enriched gel to a standard gel in the same person, measuring swelling, pain, and infection risk. Participants are healthy adults aged 18-34 with both lower wisdom teeth needing removal.
What this could mean
Our plain-language read of the trial. This is informational only — not medical advice or a prediction.
- Active substance
- Antibiotic-enriched platelet-rich fibrin (PRF), a blood-derived gel with added antibiotic, placed in the tooth socket after extraction.
- What this could lead to
- If effective, this approach could reduce pain, swelling, and infection risk after wisdom tooth surgery, potentially speeding recovery and reducing the need for oral antibiotics.
- What could go wrong
- This is a small early-stage trial, so results may not apply broadly. Risks include possible allergic reactions to the antibiotic or the procedure itself, and the added benefit over standard PRF may be minimal.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
Contacts and locations
Locations
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Magna Graecia University of Catanzaro
Catanzaro, cz, 88100, Italy
More trials for these conditions
Other studies related to the condition(s) this trial covers.
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- Can a cup of chamomile soothe Post-Tooth extraction pain?
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- Which membrane best preserves bone after tooth extraction? study seeks answer.