Engineered immune cells take on Hard-to-Treat prostate cancer

NCT ID NCT07156045

First seen Jun 27, 2026 · Last updated Jun 27, 2026

Summary

This early-phase trial tests a new cell therapy called anti-PSMA CAR NK cells in 10 people with metastatic castration-resistant prostate cancer (mCRPC), a form of prostate cancer that no longer responds to hormone therapy. The treatment uses immune cells engineered to target a protein called PSMA on cancer cells. The main goal is to check safety and side effects, with early signs of effectiveness also being measured.

What this could mean

Our plain-language read of the trial. This is informational only — not medical advice or a prediction.

Active substance

anti-PSMA CAR NK cells

What this could lead to

If it works, this could point toward a new cell therapy for advanced prostate cancer that has stopped responding to standard hormone treatment.

What could go wrong

This is a very early, small trial (10 people) focused on safety. The treatment may not shrink tumors or extend life, and there are risks of serious side effects from the cell infusion.

Disclaimer Read more

This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Conditions

The condition(s) this trial relates to.

castration-resistant prostate carcinoma metastatic prostate carcinoma

As listed by the trial registrant

The condition terms exactly as the trial's registrant entered them.

Contacts and locations

Locations

  • Cancer Hospital Chinese Academy of Medical Sciences

    RECRUITING

    Beijing, Beijing Municipality, 100000, China

    Contact Phone: •••-•••-•••• Email: •••••@•••••