Can diabetes drugs boost cancer immunotherapy? new trial investigates

NCT ID NCT04114136

First seen Apr 30, 2026 · Last updated Jun 12, 2026 · Updated 8 times

Summary

This study tests whether adding metformin or rosiglitazone (drugs that change how cells use energy) to standard immunotherapy (anti-PD-1) can help shrink tumors in people with advanced cancers like melanoma, lung, liver, or stomach cancer. About 72 participants will be randomly assigned to one of three treatment groups. The goal is to see if these combinations improve overall response and delay disease progression.

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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.

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Contacts and locations

Study contacts

  • Contact

    Phone: •••-•••-•••• Email: •••••@•••••

Locations

  • UPMC Hillman Cancer Center

    RECRUITING

    Pittsburgh, Pennsylvania, 15232, United States

    Contact

    Contact Phone: •••-•••-•••• Email: •••••@•••••

Conditions

Explore the condition pages connected to this study.