Can anti-inflammatory drugs help patients avoid lifelong insulin after pancreas surgery?
NCT ID NCT02713997
First seen Jun 27, 2026 · Last updated Jun 27, 2026
Summary
This study tested two anti-inflammatory drugs (etanercept and alpha-1 antitrypsin) in 43 adults with severe chronic pancreatitis who had their pancreas removed and their insulin-making cells (islets) transplanted into the liver. The goal was to see if these drugs could protect the transplanted cells and reduce the need for lifelong insulin. Participants were randomly assigned to receive one of the drugs or standard care, and their insulin production was measured over two years.
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This is a summary of the original study . Summaries may miss details or leave out important information. Before applying or accepting participation, make sure you have read and understood the full study. Curemydisease.com takes no responsibility whatsoever for anything missed, misunderstood, or acted upon as a result of our summary — we know it does not capture everything.
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Conditions
The condition(s) this trial relates to.
As listed by the trial registrant
The condition terms exactly as the trial's registrant entered them.
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Locations
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University of Minnesota
Minneapolis, Minnesota, 55455, United States