Can anti-inflammatory drugs help patients avoid lifelong insulin after pancreas surgery?

This study tested two anti-inflammatory drugs (etanercept and alpha-1 antitrypsin) in 43 adults with severe chronic pancreatitis who had their pancreas removed and their insulin-making cells (islets) transplanted into the liver. The goal was to see if these drugs could protect the transplanted cells and reduce the need for lifelong insulin. Participants were randomly assigned to receive one of the drugs or standard care, and their insulin production was measured over two years.