Promising drug combo targets deadly brain cancer in new trial

NCT ID NCT04959500

First seen Jan 06, 2026 · Last updated Apr 25, 2026 · Updated 17 times

Summary

This study tests whether adding anlotinib hydrochloride to the standard Stupp regimen can help people with newly diagnosed glioblastoma, an aggressive brain cancer. About 150 adults aged 18-75 will receive either the combination or standard treatment alone. The main goal is to see if the new combination delays cancer growth or improves survival.

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Contacts and locations

Locations

  • Beijing TianTan Hospital,Capital Medical University

    Beijing, Beijing Municipality, 100070, China

  • Chongqing University Cancer Hospital

    Chongqing, Chongqing Municipality, 400000, China

  • Fudan University shabghai cancer center

    Shanghai, Shanghai Municipality, 200433, China

  • Fujian Provincial Cancer Hospital

    Fuzhou, Fujian, 350014, China

  • Gansu Provincial Hospital

    Gansu, Lanzhou Province, 730000, China

  • Henan Cancer Hospital

    Zhengzhou, Henan, 450008, China

  • Jiangxi Cancer Hospital

    Nanchang, Jiangxi, 330029, China

  • Lanzhou University Second Hospital

    Lanzhou, Gansu, 730000, China

  • Liaoning Cancer Hospital & Institute

    Shenyang, Liaoning, 110042, China

  • Shenzhen People's Hospital

    Shenzhen, Guangdong, 518000, China

  • Sun Yat-sen University Cancer Center

    Guangzhou, Guangdong, 510060, China

  • The Fifth Affiliated Hospital Sun Yat-sen University

    Zhuhai, Guangdong, 519000, China

  • The First Affiliated Hospital of Bengbu Medical College

    Bengbu, Anhui, 233004, China

  • The First Affiliated Hospital of NanChang University

    Nanchang, Jiangxi, 330006, China

  • The First Hospital of Lanzhou University

    Lanzhou, Gansu, 730000, China

  • The General Hospital of the People's Liberation Army (PLAGH)

    Beijing, Beijing Municipality, 100853, China

  • The Second Affiliated Hospital of PLA Air Force Medical University

    Xian, Shanxi, 710000, China

  • The Sixth Madical Center of PLA General Hospital

    Beijing, Beijing Municipality, 100142, China

  • The affiliated hospital of xuzhou medical university

    Xuzhou, Jiangsu, 221000, China

  • Tianjin Medical University General Hospital

    Tianjin, Tianjin Municipality, 300052, China

  • West China Hospital,Sichuan University

    Chengdu, Sichuan, 610041, China

  • Zhejiang Cancer Hospital

    Hangzhou, Zhejiang, 310000, China

Conditions

Explore the condition pages connected to this study.