Two drugs better than one? study tests combo for spinal arthritis

NCT ID NCT01895764

Summary

This study tested whether adding methotrexate to the standard drug adalimumab helps reduce the body's immune reaction against the treatment in people with ankylosing spondylitis. Researchers enrolled 110 adults with active spinal arthritis who hadn't responded well to common anti-inflammatory drugs. They measured whether the drug combination resulted in fewer antibodies against adalimumab and tracked changes in disease activity.

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Contacts and locations

Locations

  • Médecine polyvalente, CH de SAINT NAZAIRE

    Saint-Nazaire, 44606, France

  • Rhumatologie / IPROS, CHR d'ORLEANS

    Orléans, 45032, France

  • Rhumatologie, CH de BLOIS

    Blois, 41000, France

  • Rhumatologie, CH de SAINT BRIEUC

    Saint-Brieuc, 22027, France

  • Rhumatologie, CHD LA ROCHE SUR YON

    La Roche-sur-Yon, 85925, France

  • Rhumatologie, CHR du MANS

    Le Mans, 72037, France

  • Rhumatologie, CHRU de BREST

    Brest, 29609, France

  • Rhumatologie, CHRU de NANTES

    Nantes, 44093, France

  • Rhumatologie, CHRU de POITIERS

    Poitiers, 86021, France

  • Rhumatologie, CHRU de RENNES

    Rennes, 35203, France

  • Rhumatologie, CHRU de TOURS

    Tours, 37044, France

Conditions

Explore the condition pages connected to this study.